TCF19 (transcription factor 19)

2016-10-01 Affiliation

Identity

HGNC

TCF19

LOCATION

6p21.33

LOCUSID

6941

ALIAS

SC1,TCF-19

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 6941
MIM: 600912
HGNC: 11629
Ensembl: ENSG00000137310

Variants:

dbSNP: 6941
ClinVar: 6941
TCGA: ENSG00000137310
COSMIC: TCF19

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000137310	ENST00000376255	Q9Y242
ENSG00000137310	ENST00000376255	A0A1U9X8M7
ENSG00000137310	ENST00000376257	Q9Y242
ENSG00000137310	ENST00000376257	A0A1U9X8M7
ENSG00000137310	ENST00000542218	H0YFN0

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

PharmGKB

Entity ID	Name	Type	Evidence	Association	PK	PD	PMIDs
PA447230	HIV	Disease	ClinicalAnnotation	associated		PD	21810746
PA450616	nevirapine	Chemical	ClinicalAnnotation	associated		PD	21810746

References

Pubmed ID	Year	Title	Citations
19851445	2009	High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.	51
23760081	2013	A genome-wide association study identified new variants associated with the risk of chronic hepatitis B.	33
23860123	2013	Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line.	12
23860123	2013	Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line.	12
21076979	2011	Conditional meta-analysis stratifying on detailed HLA genotypes identifies a novel type 1 diabetes locus around TCF19 in the MHC.	8
29042441	2017	Transcription factor 19 interacts with histone 3 lysine 4 trimethylation and controls gluconeogenesis via the nucleosome-remodeling-deacetylase complex.	4
20587610	2010	Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.	1
30509085	2019	TCF19 enhances cell proliferation in hepatocellular carcinoma by activating the ATK/FOXO1 signaling pathway.	1

Citation

Dessen P

TCF19 (transcription factor 19)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56299/tcf19