Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TCF20 (transcription factor 20)

Identity

Alias_namestranscription factor 20 (AR1)
Alias_symbol (synonym)AR1
SPBP
Other aliasDDVIBA
TCF-20
HGNC (Hugo) TCF20
LocusID (NCBI) 6942
Atlas_Id 54694
Location 22q13.2  [Link to chromosome band 22q13]
Location_base_pair Starts at 42160013 and ends at 42215341 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NF2 (22q12.2) / TCF20 (22q13.2)TCF20 (22q13.2) / MKL1 (22q13.1)TCF20 (22q13.2) / NF2 (22q12.2)
TCF20 (22q13.2) / TCF20 (22q13.2)TCF20 (22q13.2) / TM2D2 (8p11.22)UCP2 (11q13.4) / TCF20 (22q13.2)
TCF20 22q13.2 / MKL1 22q13.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 4 ]
  t(22;22)(q12;q13) NF2/TCF20
t(22;22)(q12;q13) TCF20/NF2
t(22;22)(q12;q13) TCF20/TTC28
TCF20/MKL1 (22q13)

External links

Nomenclature
HGNC (Hugo)TCF20   11631
LRG (Locus Reference Genomic)LRG_1025
Cards
Entrez_Gene (NCBI)TCF20  6942  transcription factor 20
AliasesAR1; DDVIBA; SPBP; TCF-20
GeneCards (Weizmann)TCF20
Ensembl hg19 (Hinxton)ENSG00000100207 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100207 [Gene_View]  ENSG00000100207 [Sequence]  chr22:42160013-42215341 [Contig_View]  TCF20 [Vega]
ICGC DataPortalENSG00000100207
TCGA cBioPortalTCF20
AceView (NCBI)TCF20
Genatlas (Paris)TCF20
WikiGenes6942
SOURCE (Princeton)TCF20
Genetics Home Reference (NIH)TCF20
Genomic and cartography
GoldenPath hg38 (UCSC)TCF20  -     chr22:42160013-42215341 -  22q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TCF20  -     22q13.2   [Description]    (hg19-Feb_2009)
GoldenPathTCF20 - 22q13.2 [CytoView hg19]  TCF20 - 22q13.2 [CytoView hg38]
ImmunoBaseENSG00000100207
Mapping of homologs : NCBITCF20 [Mapview hg19]  TCF20 [Mapview hg38]
OMIM603107   618430   
Gene and transcription
Genbank (Entrez)AB006630 BC013180 BU732753 KF851355 U19345
RefSeq transcript (Entrez)NM_005650 NM_181492
RefSeq genomic (Entrez)NC_000022 NG_028982 NT_187682 NW_003315971 NW_009646207 NW_009646208 NW_014040930 NW_014040931 NW_015148968
Consensus coding sequences : CCDS (NCBI)TCF20
Cluster EST : UnigeneHs.475018 [ NCBI ]
CGAP (NCI)Hs.475018
Alternative Splicing GalleryENSG00000100207
Gene ExpressionTCF20 [ NCBI-GEO ]   TCF20 [ EBI - ARRAY_EXPRESS ]   TCF20 [ SEEK ]   TCF20 [ MEM ]
Gene Expression Viewer (FireBrowse)TCF20 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6942
GTEX Portal (Tissue expression)TCF20
Human Protein AtlasENSG00000100207-TCF20 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UGU0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UGU0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UGU0
Splice isoforms : SwissVarQ9UGU0
PhosPhoSitePlusQ9UGU0
Domaine pattern : Prosite (Expaxy)EPHD (PS51805)   
Domains : Interpro (EBI)EPHD    Znf_PHD    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)PHD (SM00249)  
Conserved Domain (NCBI)TCF20
DMDM Disease mutations6942
Blocks (Seattle)TCF20
SuperfamilyQ9UGU0
Human Protein Atlas [tissue]ENSG00000100207-TCF20 [tissue]
Peptide AtlasQ9UGU0
HPRD04378
IPIIPI00159322   IPI00220381   IPI00879664   
Protein Interaction databases
DIP (DOE-UCLA)Q9UGU0
IntAct (EBI)Q9UGU0
FunCoupENSG00000100207
BioGRIDTCF20
STRING (EMBL)TCF20
ZODIACTCF20
Ontologies - Pathways
QuickGOQ9UGU0
Ontology : AmiGODNA binding  DNA-binding transcription factor activity  transcription coactivator activity  RNA binding  protein binding  nucleus  nucleus  nucleoplasm  regulation of transcription, DNA-templated  nuclear body  transcription regulatory region DNA binding  positive regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBIDNA binding  DNA-binding transcription factor activity  transcription coactivator activity  RNA binding  protein binding  nucleus  nucleus  nucleoplasm  regulation of transcription, DNA-templated  nuclear body  transcription regulatory region DNA binding  positive regulation of transcription by RNA polymerase II  metal ion binding  
NDEx NetworkTCF20
Atlas of Cancer Signalling NetworkTCF20
Wikipedia pathwaysTCF20
Orthology - Evolution
OrthoDB6942
GeneTree (enSembl)ENSG00000100207
Phylogenetic Trees/Animal Genes : TreeFamTCF20
HOGENOMQ9UGU0
Homologs : HomoloGeneTCF20
Homology/Alignments : Family Browser (UCSC)TCF20
Gene fusions - Rearrangements
Fusion : MitelmanNF2/TCF20 [22q12.2/22q13.2]  [t(22;22)(q12;q13)]  
Fusion : MitelmanTCF20/MKL1 [22q13.2/22q13.1]  [t(22;22)(q13;q13)]  
Fusion : MitelmanTCF20/NF2 [22q13.2/22q12.2]  [t(22;22)(q12;q13)]  
Fusion PortalTCF20 22q13.2 MKL1 22q13.1 LUAD
Fusion : QuiverTCF20
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTCF20 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TCF20
dbVarTCF20
ClinVarTCF20
1000_GenomesTCF20 
Exome Variant ServerTCF20
ExAC (Exome Aggregation Consortium)ENSG00000100207
GNOMAD BrowserENSG00000100207
Varsome BrowserTCF20
Genetic variants : HAPMAP6942
Genomic Variants (DGV)TCF20 [DGVbeta]
DECIPHERTCF20 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTCF20 
Mutations
ICGC Data PortalTCF20 
TCGA Data PortalTCF20 
Broad Tumor PortalTCF20
OASIS PortalTCF20 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTCF20  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTCF20
Mutations and Diseases : HGMDTCF20
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TCF20
DgiDB (Drug Gene Interaction Database)TCF20
DoCM (Curated mutations)TCF20 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TCF20 (select a term)
intoGenTCF20
Cancer3DTCF20(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603107    618430   
Orphanet
DisGeNETTCF20
MedgenTCF20
Genetic Testing Registry TCF20
NextProtQ9UGU0 [Medical]
TSGene6942
GENETestsTCF20
Target ValidationTCF20
Huge Navigator TCF20 [HugePedia]
snp3D : Map Gene to Disease6942
BioCentury BCIQTCF20
ClinGenTCF20
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6942
Chemical/Pharm GKB GenePA36386
Clinical trialTCF20
Miscellaneous
canSAR (ICR)TCF20 (select the gene name)
DataMed IndexTCF20
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTCF20
EVEXTCF20
GoPubMedTCF20
iHOPTCF20
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 18:11:09 CET 2019
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