TENT4B (terminal nucleotidyltransferase 4B)

2014-01-01  

Identity

HGNC
LOCATION
16q12.1
LOCUSID
ALIAS
PAPD5,TRF4-2,TUT3

Other Information

Locus ID:

NCBI: 64282
MIM: 605540
HGNC: 30758
Ensembl: ENSG00000121274

Variants:

dbSNP: 64282
ClinVar: 64282
TCGA: ENSG00000121274
COSMIC: TENT4B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000121274ENST00000357464E9PC61
ENSG00000121274ENST00000436909Q8NDF8
ENSG00000121274ENST00000561678G4U4J3
ENSG00000121274ENST00000561678H3BQM0

Pathways

PathwaySourceExternal ID
RNA degradationKEGGko03018
RNA degradationKEGGhsa03018
TRAMP complexKEGGhsa_M00393
TRAMP complexKEGGM00393

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
250494172014PAPD5-mediated 3' adenylation and subsequent degradation of miR-21 is disrupted in proliferative disease.50
217883342011PAPD5, a noncanonical poly(A) polymerase with an unusual RNA-binding motif.31
300263172018Mixed tailing by TENT4A and TENT4B shields mRNA from rapid deadenylation.20
309300562019Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease.10
274348182016Interaction properties of human TRAMP-like proteins and their role in pre-rRNA 5'ETS turnover.7
283837162017Essential role for non-canonical poly(A) polymerase GLD4 in cytoplasmic polyadenylation and carbohydrate metabolism.2

Citation

Dessen P

TENT4B (terminal nucleotidyltransferase 4B)

Atlas Genet Cytogenet Oncol Haematol. 2014-01-01

Online version: http://atlasgeneticsoncology.org/gene/53652/tent4b