Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TFB2M (transcription factor B2, mitochondrial)

Identity

Alias_symbol (synonym)FLJ23182
FLJ22661
Hkp1
Other aliasmtTFB2
HGNC (Hugo) TFB2M
LocusID (NCBI) 64216
Atlas_Id 54698
Location 1q44  [Link to chromosome band 1q44]
Location_base_pair Starts at 246540561 and ends at 246566263 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SMYD3 (1q44) / TFB2M (1q44)SMYD3 1q44 / TFB2M 1q44

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  del(1)(q44q44) ZNF695/TFB2M


External links

Nomenclature
HGNC (Hugo)TFB2M   18559
Cards
Entrez_Gene (NCBI)TFB2M  64216  transcription factor B2, mitochondrial
AliasesHkp1; mtTFB2
GeneCards (Weizmann)TFB2M
Ensembl hg19 (Hinxton)ENSG00000162851 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162851 [Gene_View]  ENSG00000162851 [Sequence]  chr1:246540561-246566263 [Contig_View]  TFB2M [Vega]
ICGC DataPortalENSG00000162851
TCGA cBioPortalTFB2M
AceView (NCBI)TFB2M
Genatlas (Paris)TFB2M
WikiGenes64216
SOURCE (Princeton)TFB2M
Genetics Home Reference (NIH)TFB2M
Genomic and cartography
GoldenPath hg38 (UCSC)TFB2M  -     chr1:246540561-246566263 -  1q44   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TFB2M  -     1q44   [Description]    (hg19-Feb_2009)
GoldenPathTFB2M - 1q44 [CytoView hg19]  TFB2M - 1q44 [CytoView hg38]
ImmunoBaseENSG00000162851
Mapping of homologs : NCBITFB2M [Mapview hg19]  TFB2M [Mapview hg38]
OMIM607055   
Gene and transcription
Genbank (Entrez)AF529366 AK026314 AK026835 AK300238 BC003383
RefSeq transcript (Entrez)NM_022366
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TFB2M
Cluster EST : UnigeneHs.7395 [ NCBI ]
CGAP (NCI)Hs.7395
Alternative Splicing GalleryENSG00000162851
Gene ExpressionTFB2M [ NCBI-GEO ]   TFB2M [ EBI - ARRAY_EXPRESS ]   TFB2M [ SEEK ]   TFB2M [ MEM ]
Gene Expression Viewer (FireBrowse)TFB2M [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64216
GTEX Portal (Tissue expression)TFB2M
Human Protein AtlasENSG00000162851-TFB2M [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H5Q4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H5Q4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H5Q4
Splice isoforms : SwissVarQ9H5Q4
PhosPhoSitePlusQ9H5Q4
Domaine pattern : Prosite (Expaxy)SAM_RNA_A_N6_MT (PS51689)   
Domains : Interpro (EBI)KsgA/Erm    rRNA_Ade_methylase_Trfase_N    SAM-dependent_MTases    TFB2M   
Domain families : Pfam (Sanger)RrnaAD (PF00398)   
Domain families : Pfam (NCBI)pfam00398   
Domain families : Smart (EMBL)rADc (SM00650)  
Conserved Domain (NCBI)TFB2M
DMDM Disease mutations64216
Blocks (Seattle)TFB2M
PDB (RSDB)6ERO    6ERP    6ERQ   
PDB Europe6ERO    6ERP    6ERQ   
PDB (PDBSum)6ERO    6ERP    6ERQ   
PDB (IMB)6ERO    6ERP    6ERQ   
Structural Biology KnowledgeBase6ERO    6ERP    6ERQ   
SCOP (Structural Classification of Proteins)6ERO    6ERP    6ERQ   
CATH (Classification of proteins structures)6ERO    6ERP    6ERQ   
SuperfamilyQ9H5Q4
Human Protein Atlas [tissue]ENSG00000162851-TFB2M [tissue]
Peptide AtlasQ9H5Q4
HPRD09520
IPIIPI00034069   IPI01015117   
Protein Interaction databases
DIP (DOE-UCLA)Q9H5Q4
IntAct (EBI)Q9H5Q4
FunCoupENSG00000162851
BioGRIDTFB2M
STRING (EMBL)TFB2M
ZODIACTFB2M
Ontologies - Pathways
QuickGOQ9H5Q4
Ontology : AmiGOrRNA (adenine-N6,N6-)-dimethyltransferase activity  transcription coregulator activity  RNA binding  mitochondrion  mitochondrial matrix  mitochondrial matrix  mitochondrial matrix  mitochondrial transcription  mitochondrial transcription  transcription initiation from mitochondrial promoter  transcription initiation from mitochondrial promoter  mitochondrion organization  rRNA methylation  mitochondrial nucleoid  positive regulation of transcription, DNA-templated  
Ontology : EGO-EBIrRNA (adenine-N6,N6-)-dimethyltransferase activity  transcription coregulator activity  RNA binding  mitochondrion  mitochondrial matrix  mitochondrial matrix  mitochondrial matrix  mitochondrial transcription  mitochondrial transcription  transcription initiation from mitochondrial promoter  transcription initiation from mitochondrial promoter  mitochondrion organization  rRNA methylation  mitochondrial nucleoid  positive regulation of transcription, DNA-templated  
NDEx NetworkTFB2M
Atlas of Cancer Signalling NetworkTFB2M
Wikipedia pathwaysTFB2M
Orthology - Evolution
OrthoDB64216
GeneTree (enSembl)ENSG00000162851
Phylogenetic Trees/Animal Genes : TreeFamTFB2M
HOGENOMQ9H5Q4
Homologs : HomoloGeneTFB2M
Homology/Alignments : Family Browser (UCSC)TFB2M
Gene fusions - Rearrangements
Fusion PortalSMYD3 1q44 TFB2M 1q44 BRCA
Fusion : QuiverTFB2M
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTFB2M [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TFB2M
dbVarTFB2M
ClinVarTFB2M
1000_GenomesTFB2M 
Exome Variant ServerTFB2M
ExAC (Exome Aggregation Consortium)ENSG00000162851
GNOMAD BrowserENSG00000162851
Varsome BrowserTFB2M
Genetic variants : HAPMAP64216
Genomic Variants (DGV)TFB2M [DGVbeta]
DECIPHERTFB2M [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTFB2M 
Mutations
ICGC Data PortalTFB2M 
TCGA Data PortalTFB2M 
Broad Tumor PortalTFB2M
OASIS PortalTFB2M [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTFB2M  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTFB2M
Mutations and Diseases : HGMDTFB2M
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch TFB2M
DgiDB (Drug Gene Interaction Database)TFB2M
DoCM (Curated mutations)TFB2M (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TFB2M (select a term)
intoGenTFB2M
Cancer3DTFB2M(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607055   
Orphanet
DisGeNETTFB2M
MedgenTFB2M
Genetic Testing Registry TFB2M
NextProtQ9H5Q4 [Medical]
TSGene64216
GENETestsTFB2M
Target ValidationTFB2M
Huge Navigator TFB2M [HugePedia]
snp3D : Map Gene to Disease64216
BioCentury BCIQTFB2M
ClinGenTFB2M
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64216
Chemical/Pharm GKB GenePA38348
Clinical trialTFB2M
Miscellaneous
canSAR (ICR)TFB2M (select the gene name)
DataMed IndexTFB2M
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTFB2M
EVEXTFB2M
GoPubMedTFB2M
iHOPTFB2M
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 18:11:29 CET 2019

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.