Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7036
MIM: 604720
HGNC: 11762
Ensembl: ENSG00000106327
Variants:
dbSNP: 7036
ClinVar: 7036
TCGA: ENSG00000106327
COSMIC: TFR2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000106327 | ENST00000223051 | Q9UP52 |
| ENSG00000106327 | ENST00000431692 | E7ET36 |
| ENSG00000106327 | ENST00000462107 | Q9UP52 |
| ENSG00000106327 | ENST00000490084 | H7C544 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36702193 | 2023 | TFR2 regulates ferroptosis and enhances temozolomide chemo-sensitization in gliomas. | 8 |
| 37480032 | 2023 | Circ-STC2 promotes the ferroptosis of nucleus pulposus cells via targeting miR-486-3p/TFR2 axis. | 0 |
| 36702193 | 2023 | TFR2 regulates ferroptosis and enhances temozolomide chemo-sensitization in gliomas. | 8 |
| 37480032 | 2023 | Circ-STC2 promotes the ferroptosis of nucleus pulposus cells via targeting miR-486-3p/TFR2 axis. | 0 |
| 35225679 | 2022 | Estimates of West African Ancestry in African Americans Using Alleles of Iron-Related Genes HJV, SLC40A1, and TFR2. | 0 |
| 35705926 | 2022 | Assessment of iron overload in a cohort of Sri Lankan patients with transfusion dependent beta thalassaemia and its correlation with pathogenic variants in HBB, HFE, SLC40A1, and TFR2 genes. | 2 |
| 35225679 | 2022 | Estimates of West African Ancestry in African Americans Using Alleles of Iron-Related Genes HJV, SLC40A1, and TFR2. | 0 |
| 35705926 | 2022 | Assessment of iron overload in a cohort of Sri Lankan patients with transfusion dependent beta thalassaemia and its correlation with pathogenic variants in HBB, HFE, SLC40A1, and TFR2 genes. | 2 |
| 34077792 | 2021 | Iron-loaded transferrin potentiates erythropoietin effects on erythroblast proliferation and survival: a novel role through transferrin receptors. | 5 |
| 34199599 | 2021 | Orphan Nuclear Receptor ERRγ Is a Transcriptional Regulator of CB1 Receptor-Mediated TFR2 Gene Expression in Hepatocytes. | 1 |
| 34946929 | 2021 | New Mutations in HFE2 and TFR2 Genes Causing Non HFE-Related Hereditary Hemochromatosis. | 1 |
| 35355750 | 2021 | Evaluation of the Association of Transferrin Receptor Type 2 Gene Mutation (Y250X) with Iron Overload in Major β- Thalassemia. | 0 |
| 34077792 | 2021 | Iron-loaded transferrin potentiates erythropoietin effects on erythroblast proliferation and survival: a novel role through transferrin receptors. | 5 |
| 34199599 | 2021 | Orphan Nuclear Receptor ERRγ Is a Transcriptional Regulator of CB1 Receptor-Mediated TFR2 Gene Expression in Hepatocytes. | 1 |
| 34946929 | 2021 | New Mutations in HFE2 and TFR2 Genes Causing Non HFE-Related Hereditary Hemochromatosis. | 1 |
Citation
Dessen P
TFR2 (transferrin receptor 2)
Atlas Genet Cytogenet Oncol Haematol. 2010-01-01
Online version: http://atlasgeneticsoncology.org/gene/51246/tfr2
