Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7039
MIM: 190170
HGNC: 11765
Ensembl: ENSG00000163235
Variants:
dbSNP: 7039
ClinVar: 7039
TCGA: ENSG00000163235
COSMIC: TGFA
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10040 | cetuximab | Chemical | Pathway | associated | |||
| PA162373091 | panitumumab | Chemical | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38152044 | 2024 | TGFA expression is associated with poor prognosis and promotes the development of cervical cancer. | 1 |
| 38152044 | 2024 | TGFA expression is associated with poor prognosis and promotes the development of cervical cancer. | 1 |
| 37686213 | 2023 | EGF, TGF-α and Amphiregulin Differently Regulate Endometrium-Derived Mesenchymal Stromal/Stem Cells. | 1 |
| 37686213 | 2023 | EGF, TGF-α and Amphiregulin Differently Regulate Endometrium-Derived Mesenchymal Stromal/Stem Cells. | 1 |
| 35075162 | 2022 | Genetic markers for non-syndromic orofacial clefts in populations of European ancestry: a meta-analysis. | 5 |
| 35804263 | 2022 | CircRTN1 acts as a miR-431-5p sponge to promote thyroid cancer progression by upregulating TGFA. | 0 |
| 36068759 | 2022 | Autocrine TGF-alpha is associated with Benzo(a)pyrene-induced mucus production and MUC5AC expression during allergic asthma. | 3 |
| 35075162 | 2022 | Genetic markers for non-syndromic orofacial clefts in populations of European ancestry: a meta-analysis. | 5 |
| 35804263 | 2022 | CircRTN1 acts as a miR-431-5p sponge to promote thyroid cancer progression by upregulating TGFA. | 0 |
| 36068759 | 2022 | Autocrine TGF-alpha is associated with Benzo(a)pyrene-induced mucus production and MUC5AC expression during allergic asthma. | 3 |
| 33200192 | 2021 | IRF6, MSX1, TGFA, dental anomalies, and skeletal malocclusion. | 3 |
| 33480984 | 2021 | MicroRNA-374b inhibits breast cancer progression through regulating CCND1 and TGFA genes. | 7 |
| 33661995 | 2021 | LncRNA LINC00857 strengthens the malignancy behaviors of pancreatic adenocarcinoma cells by serving as a competing endogenous RNA for miR-340-5p to upregulate TGFA expression. | 10 |
| 34301821 | 2021 | The Aryl Hydrocarbon Receptor-Dependent TGF-α/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis. | 7 |
| 34399807 | 2021 | Altered proTGFα/cleaved TGFα ratios offer new therapeutic strategies in renal carcinoma. | 0 |
Citation
Dessen P
TGFA (transforming growth factor alpha)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/32/tgfa
