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THAP3 (THAP domain containing 3)

Identity

Alias_namesTHAP domain containing, apoptosis associated protein 3
Other alias-
HGNC (Hugo) THAP3
LocusID (NCBI) 90326
Atlas_Id 74666
Location 1p36.31  [Link to chromosome band 1p36]
Location_base_pair Starts at 6625150 and ends at 6633582 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CAMTA1 (1p36.31) / THAP3 (1p36.31)THAP3 (1p36.31) / SNRK (3p22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)THAP3   20855
Cards
Entrez_Gene (NCBI)THAP3  90326  THAP domain containing 3
Aliases
GeneCards (Weizmann)THAP3
Ensembl hg19 (Hinxton)ENSG00000041988 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000041988 [Gene_View]  ENSG00000041988 [Sequence]  chr1:6625150-6633582 [Contig_View]  THAP3 [Vega]
ICGC DataPortalENSG00000041988
TCGA cBioPortalTHAP3
AceView (NCBI)THAP3
Genatlas (Paris)THAP3
WikiGenes90326
SOURCE (Princeton)THAP3
Genetics Home Reference (NIH)THAP3
Genomic and cartography
GoldenPath hg38 (UCSC)THAP3  -     chr1:6625150-6633582 +  1p36.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)THAP3  -     1p36.31   [Description]    (hg19-Feb_2009)
GoldenPathTHAP3 - 1p36.31 [CytoView hg19]  THAP3 - 1p36.31 [CytoView hg38]
ImmunoBaseENSG00000041988
Mapping of homologs : NCBITHAP3 [Mapview hg19]  THAP3 [Mapview hg38]
OMIM612532   
Gene and transcription
Genbank (Entrez)AF086370 AK096217 BC005114 BC022081 BC092427
RefSeq transcript (Entrez)NM_001195752 NM_001195753 NM_138350
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)THAP3
Cluster EST : UnigeneHs.689006 [ NCBI ]
CGAP (NCI)Hs.689006
Alternative Splicing GalleryENSG00000041988
Gene ExpressionTHAP3 [ NCBI-GEO ]   THAP3 [ EBI - ARRAY_EXPRESS ]   THAP3 [ SEEK ]   THAP3 [ MEM ]
Gene Expression Viewer (FireBrowse)THAP3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)90326
GTEX Portal (Tissue expression)THAP3
Human Protein AtlasENSG00000041988-THAP3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WTV1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WTV1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WTV1
Splice isoforms : SwissVarQ8WTV1
PhosPhoSitePlusQ8WTV1
Domaine pattern : Prosite (Expaxy)ZF_THAP (PS50950)   
Domains : Interpro (EBI)THAP3    THAP_Znf    THAP_Znf_sf   
Domain families : Pfam (Sanger)THAP (PF05485)   
Domain families : Pfam (NCBI)pfam05485   
Domain families : Smart (EMBL)DM3 (SM00692)  THAP (SM00980)  
Conserved Domain (NCBI)THAP3
DMDM Disease mutations90326
Blocks (Seattle)THAP3
SuperfamilyQ8WTV1
Human Protein Atlas [tissue]ENSG00000041988-THAP3 [tissue]
Peptide AtlasQ8WTV1
HPRD18178
IPIIPI00008242   IPI00643983   IPI00167574   
Protein Interaction databases
DIP (DOE-UCLA)Q8WTV1
IntAct (EBI)Q8WTV1
FunCoupENSG00000041988
BioGRIDTHAP3
STRING (EMBL)THAP3
ZODIACTHAP3
Ontologies - Pathways
QuickGOQ8WTV1
Ontology : AmiGODNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  protein binding  regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBIDNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  protein binding  regulation of transcription by RNA polymerase II  metal ion binding  
NDEx NetworkTHAP3
Atlas of Cancer Signalling NetworkTHAP3
Wikipedia pathwaysTHAP3
Orthology - Evolution
OrthoDB90326
GeneTree (enSembl)ENSG00000041988
Phylogenetic Trees/Animal Genes : TreeFamTHAP3
HOGENOMQ8WTV1
Homologs : HomoloGeneTHAP3
Homology/Alignments : Family Browser (UCSC)THAP3
Gene fusions - Rearrangements
Fusion : QuiverTHAP3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTHAP3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)THAP3
dbVarTHAP3
ClinVarTHAP3
1000_GenomesTHAP3 
Exome Variant ServerTHAP3
ExAC (Exome Aggregation Consortium)ENSG00000041988
GNOMAD BrowserENSG00000041988
Varsome BrowserTHAP3
Genetic variants : HAPMAP90326
Genomic Variants (DGV)THAP3 [DGVbeta]
DECIPHERTHAP3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTHAP3 
Mutations
ICGC Data PortalTHAP3 
TCGA Data PortalTHAP3 
Broad Tumor PortalTHAP3
OASIS PortalTHAP3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTHAP3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTHAP3
Mutations and Diseases : HGMDTHAP3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch THAP3
DgiDB (Drug Gene Interaction Database)THAP3
DoCM (Curated mutations)THAP3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)THAP3 (select a term)
intoGenTHAP3
Cancer3DTHAP3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612532   
Orphanet
DisGeNETTHAP3
MedgenTHAP3
Genetic Testing Registry THAP3
NextProtQ8WTV1 [Medical]
TSGene90326
GENETestsTHAP3
Target ValidationTHAP3
Huge Navigator THAP3 [HugePedia]
snp3D : Map Gene to Disease90326
BioCentury BCIQTHAP3
ClinGenTHAP3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD90326
Chemical/Pharm GKB GenePA134987111
Clinical trialTHAP3
Miscellaneous
canSAR (ICR)THAP3 (select the gene name)
DataMed IndexTHAP3
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTHAP3
EVEXTHAP3
GoPubMedTHAP3
iHOPTHAP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 16:09:52 CEST 2019
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