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THAP4 (THAP domain containing 4)

Identity

Alias_symbol (synonym)CGI-36
Other aliasNb(III)
PP238
HGNC (Hugo) THAP4
LocusID (NCBI) 51078
Atlas_Id 74667
Location 2q37.3  [Link to chromosome band 2q37]
Location_base_pair Starts at 241584405 and ends at 241617501 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FARP2 (2q37.3) / THAP4 (2q37.3)FOXN2 (2p16.3) / THAP4 (2q37.3)NTPCR (1q42.2) / THAP4 (2q37.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)THAP4   23187
Cards
Entrez_Gene (NCBI)THAP4  51078  THAP domain containing 4
AliasesCGI-36; Nb(III); PP238
GeneCards (Weizmann)THAP4
Ensembl hg19 (Hinxton)ENSG00000176946 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176946 [Gene_View]  ENSG00000176946 [Sequence]  chr2:241584405-241617501 [Contig_View]  THAP4 [Vega]
ICGC DataPortalENSG00000176946
TCGA cBioPortalTHAP4
AceView (NCBI)THAP4
Genatlas (Paris)THAP4
WikiGenes51078
SOURCE (Princeton)THAP4
Genetics Home Reference (NIH)THAP4
Genomic and cartography
GoldenPath hg38 (UCSC)THAP4  -     chr2:241584405-241617501 -  2q37.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)THAP4  -     2q37.3   [Description]    (hg19-Feb_2009)
GoldenPathTHAP4 - 2q37.3 [CytoView hg19]  THAP4 - 2q37.3 [CytoView hg38]
ImmunoBaseENSG00000176946
Mapping of homologs : NCBITHAP4 [Mapview hg19]  THAP4 [Mapview hg38]
OMIM612533   
Gene and transcription
Genbank (Entrez)AF132970 AF258556 AK001216 AK225608 BC000247
RefSeq transcript (Entrez)NM_001164356 NM_015963
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)THAP4
Cluster EST : UnigeneHs.435759 [ NCBI ]
CGAP (NCI)Hs.435759
Alternative Splicing GalleryENSG00000176946
Gene ExpressionTHAP4 [ NCBI-GEO ]   THAP4 [ EBI - ARRAY_EXPRESS ]   THAP4 [ SEEK ]   THAP4 [ MEM ]
Gene Expression Viewer (FireBrowse)THAP4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51078
GTEX Portal (Tissue expression)THAP4
Human Protein AtlasENSG00000176946-THAP4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WY91   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WY91  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WY91
Splice isoforms : SwissVarQ8WY91
PhosPhoSitePlusQ8WY91
Domaine pattern : Prosite (Expaxy)ZF_THAP (PS50950)   
Domains : Interpro (EBI)Calycin    DUF1794    THAP_Znf    THAP_Znf_sf   
Domain families : Pfam (Sanger)DUF1794 (PF08768)    THAP (PF05485)   
Domain families : Pfam (NCBI)pfam08768    pfam05485   
Domain families : Smart (EMBL)DM3 (SM00692)  THAP (SM00980)  
Conserved Domain (NCBI)THAP4
DMDM Disease mutations51078
Blocks (Seattle)THAP4
PDB (RSDB)3IA8   
PDB Europe3IA8   
PDB (PDBSum)3IA8   
PDB (IMB)3IA8   
Structural Biology KnowledgeBase3IA8   
SCOP (Structural Classification of Proteins)3IA8   
CATH (Classification of proteins structures)3IA8   
SuperfamilyQ8WY91
Human Protein Atlas [tissue]ENSG00000176946-THAP4 [tissue]
Peptide AtlasQ8WY91
HPRD11630
IPIIPI00788055   IPI00887001   IPI01009608   IPI00894493   
Protein Interaction databases
DIP (DOE-UCLA)Q8WY91
IntAct (EBI)Q8WY91
FunCoupENSG00000176946
BioGRIDTHAP4
STRING (EMBL)THAP4
ZODIACTHAP4
Ontologies - Pathways
QuickGOQ8WY91
Ontology : AmiGODNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  cellular_component  regulation of transcription by RNA polymerase II  biological_process  heme binding  protein homodimerization activity  metal ion binding  
Ontology : EGO-EBIDNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  cellular_component  regulation of transcription by RNA polymerase II  biological_process  heme binding  protein homodimerization activity  metal ion binding  
NDEx NetworkTHAP4
Atlas of Cancer Signalling NetworkTHAP4
Wikipedia pathwaysTHAP4
Orthology - Evolution
OrthoDB51078
GeneTree (enSembl)ENSG00000176946
Phylogenetic Trees/Animal Genes : TreeFamTHAP4
HOGENOMQ8WY91
Homologs : HomoloGeneTHAP4
Homology/Alignments : Family Browser (UCSC)THAP4
Gene fusions - Rearrangements
Fusion : QuiverTHAP4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTHAP4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)THAP4
dbVarTHAP4
ClinVarTHAP4
1000_GenomesTHAP4 
Exome Variant ServerTHAP4
ExAC (Exome Aggregation Consortium)ENSG00000176946
GNOMAD BrowserENSG00000176946
Varsome BrowserTHAP4
Genetic variants : HAPMAP51078
Genomic Variants (DGV)THAP4 [DGVbeta]
DECIPHERTHAP4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTHAP4 
Mutations
ICGC Data PortalTHAP4 
TCGA Data PortalTHAP4 
Broad Tumor PortalTHAP4
OASIS PortalTHAP4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTHAP4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTHAP4
Mutations and Diseases : HGMDTHAP4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch THAP4
DgiDB (Drug Gene Interaction Database)THAP4
DoCM (Curated mutations)THAP4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)THAP4 (select a term)
intoGenTHAP4
Cancer3DTHAP4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612533   
Orphanet
DisGeNETTHAP4
MedgenTHAP4
Genetic Testing Registry THAP4
NextProtQ8WY91 [Medical]
TSGene51078
GENETestsTHAP4
Target ValidationTHAP4
Huge Navigator THAP4 [HugePedia]
snp3D : Map Gene to Disease51078
BioCentury BCIQTHAP4
ClinGenTHAP4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51078
Chemical/Pharm GKB GenePA134864723
Clinical trialTHAP4
Miscellaneous
canSAR (ICR)THAP4 (select the gene name)
DataMed IndexTHAP4
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTHAP4
EVEXTHAP4
GoPubMedTHAP4
iHOPTHAP4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 16:09:52 CEST 2019
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