Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7056
MIM: 188040
HGNC: 11784
Ensembl: ENSG00000178726
Variants:
dbSNP: 7056
ClinVar: 7056
TCGA: ENSG00000178726
COSMIC: THBD
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000178726 | ENST00000377103 | P07204 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA451906 | warfarin | Chemical | ClinicalAnnotation | associated | PD | 24602049 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37979949 | 2024 | Novel nucleotide variations in the thrombomodulin (THBD) gene involved in coagulation pathways can increase the risk of recurrent pregnancy loss (RPL). | 0 |
| 38081783 | 2024 | The role of thrombomodulin in modulating ITGB3 expression and its implications for triple-negative breast cancer progression. | 0 |
| 38174561 | 2024 | Thrombomodulin Switches Signaling and Protease-Activated Receptor 1 Cleavage Specificity of Thrombin. | 1 |
| 38330539 | 2024 | Altered release of thrombomodulin and HMGB1 in the placenta complicated with preeclampsia. | 0 |
| 38373411 | 2024 | Thrombomodulin Gene Mutation and Associated Predisposing Factors in Familial Collapsing Glomerulopathy. | 0 |
| 37979949 | 2024 | Novel nucleotide variations in the thrombomodulin (THBD) gene involved in coagulation pathways can increase the risk of recurrent pregnancy loss (RPL). | 0 |
| 38081783 | 2024 | The role of thrombomodulin in modulating ITGB3 expression and its implications for triple-negative breast cancer progression. | 0 |
| 38174561 | 2024 | Thrombomodulin Switches Signaling and Protease-Activated Receptor 1 Cleavage Specificity of Thrombin. | 1 |
| 38330539 | 2024 | Altered release of thrombomodulin and HMGB1 in the placenta complicated with preeclampsia. | 0 |
| 38373411 | 2024 | Thrombomodulin Gene Mutation and Associated Predisposing Factors in Familial Collapsing Glomerulopathy. | 0 |
| 35921923 | 2023 | A missense mutation in lectin domain of thrombomodulin causing functional deficiency. | 1 |
| 37567446 | 2023 | On the relevance of thrombomodulin variants in atypical hemolytic uremic syndrome. | 0 |
| 38057335 | 2023 | Variation in presepsin and thrombomodulin levels for predicting COVID-19 mortality. | 1 |
| 35921923 | 2023 | A missense mutation in lectin domain of thrombomodulin causing functional deficiency. | 1 |
| 37567446 | 2023 | On the relevance of thrombomodulin variants in atypical hemolytic uremic syndrome. | 0 |
Citation
Dessen P
THBD (thrombomodulin)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45938/thbd
