THNSL2 (threonine synthase like 2)

2014-11-01  

Identity

HGNC
LOCATION
2p11.2
LOCUSID
ALIAS
SOFAT,THS2,TSH2
FUSION GENES

Other Information

Locus ID:

NCBI: 55258
MIM: 611261
HGNC: 25602
Ensembl: ENSG00000144115

Variants:

dbSNP: 55258
ClinVar: 55258
TCGA: ENSG00000144115
COSMIC: THNSL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144115ENST00000324166Q86YJ6
ENSG00000144115ENST00000343544Q86YJ6
ENSG00000144115ENST00000377254A8K0C1
ENSG00000144115ENST00000419759C9J3J1
ENSG00000144115ENST00000449349C9JU10

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
198770522009A novel T cell cytokine, secreted osteoclastogenic factor of activated T cells, induces osteoclast formation in a RANKL-independent manner.30
264809202016Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat.30
212998922011Bimodal distribution of RNA expression levels in human skeletal muscle tissue.18
236194712013Secreted osteoclastogenic factor of activated T cells (SOFAT), a novel osteoclast activator, in chronic periodontitis.10
270358492016Expression of SOFAT by T- and B-lineage cells may contribute to bone loss.4
259166772015In vitro evaluation of the biological effect of SOFAT on osteoblasts.3
294895072019SOFAT as a Putative Marker of Osteoclasts in Bone Lesions.0

Citation

Dessen P

THNSL2 (threonine synthase like 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74678/thnsl2