THOC3 (THO complex 3)

2014-11-01  

Identity

HGNC
LOCATION
5q35.2
LOCUSID
ALIAS
THO3,hTREX45
FUSION GENES

Other Information

Locus ID:

NCBI: 84321
MIM: 606929
HGNC: 19072
Ensembl: ENSG00000051596

Variants:

dbSNP: 84321
ClinVar: 84321
TCGA: ENSG00000051596
COSMIC: THOC3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000051596ENST00000265097Q96J01
ENSG00000051596ENST00000432305H7C0C5
ENSG00000051596ENST00000505969H0Y9T1
ENSG00000051596ENST00000511062H0YAG7
ENSG00000051596ENST00000513006D6RGZ2
ENSG00000051596ENST00000513482Q96J01
ENSG00000051596ENST00000514250H0YAJ0
ENSG00000051596ENST00000514861D6REC9
ENSG00000051596ENST00000515016H0YA11
ENSG00000051596ENST00000628318D6RGZ2

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040
RNA transportKEGGko03013
RNA transportKEGGhsa03013
TREX complexKEGGhsa_M00406
TREX complexKEGGM00406
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Transcription TerminationREACTOMER-HSA-73856
Cleavage of Growing Transcript in the Termination RegionREACTOMER-HSA-109688
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA 3'-end processingREACTOMER-HSA-72187
Transport of Mature Transcript to CytoplasmREACTOMER-HSA-72202
Transport of Mature mRNA derived from an Intron-Containing TranscriptREACTOMER-HSA-159236

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
159988062005Recruitment of the human TREX complex to mRNA during splicing.174

Citation

Dessen P

THOC3 (THO complex 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74680/thoc3