Atlas of Genetics and Cytogenetics in Oncology and Haematology

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THOC7 (THO complex 7)

Identity

Alias (NCBI)NIF3L1BP1
fSAP24
hTREX30
HGNC (Hugo) THOC7
HGNC Alias symbNIF3L1BP1
FLJ23445
fSAP24
HGNC Alias nameNgg1 interacting factor 3 like 1 binding protein 1
 functional spliceosome-associated protein 24
HGNC Previous nameTHO complex 7 homolog (Drosophila)
LocusID (NCBI) 80145
Atlas_Id 74682
Location 3p14.1  [Link to chromosome band 3p14]
Location_base_pair Starts at 63833870 and ends at 63863923 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ATXN7 (3p14.1) / THOC7 (3p14.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)THOC7   29874
Cards
Entrez_Gene (NCBI)THOC7  80145  THO complex 7
AliasesNIF3L1BP1; fSAP24; hTREX30
GeneCards (Weizmann)THOC7
Ensembl hg19 (Hinxton)ENSG00000163634 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163634 [Gene_View]  ENSG00000163634 [Sequence]  chr3:63833870-63863923 [Contig_View]  THOC7 [Vega]
ICGC DataPortalENSG00000163634
TCGA cBioPortalTHOC7
AceView (NCBI)THOC7
Genatlas (Paris)THOC7
WikiGenes80145
SOURCE (Princeton)THOC7
Genetics Home Reference (NIH)THOC7
Genomic and cartography
GoldenPath hg38 (UCSC)THOC7  -     chr3:63833870-63863923 -  3p14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)THOC7  -     3p14.1   [Description]    (hg19-Feb_2009)
GoldenPathTHOC7 - 3p14.1 [CytoView hg19]  THOC7 - 3p14.1 [CytoView hg38]
ImmunoBaseENSG00000163634
genome Data Viewer NCBITHOC7 [Mapview hg19]  
OMIM611965   
Gene and transcription
Genbank (Entrez)AF104914 AI391685 AI784549 AK027098 AK225110
RefSeq transcript (Entrez)NM_001285387 NM_001285404 NM_025075
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)THOC7
Alternative Splicing GalleryENSG00000163634
Gene ExpressionTHOC7 [ NCBI-GEO ]   THOC7 [ EBI - ARRAY_EXPRESS ]   THOC7 [ SEEK ]   THOC7 [ MEM ]
Gene Expression Viewer (FireBrowse)THOC7 [ Firebrowse - Broad ]
GenevisibleExpression of THOC7 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80145
GTEX Portal (Tissue expression)THOC7
Human Protein AtlasENSG00000163634-THOC7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6I9Y2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6I9Y2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6I9Y2
Splice isoforms : SwissVarQ6I9Y2
PhosPhoSitePlusQ6I9Y2
Domains : Interpro (EBI)THOC7/Mft1   
Domain families : Pfam (Sanger)THOC7 (PF05615)   
Domain families : Pfam (NCBI)pfam05615   
Conserved Domain (NCBI)THOC7
DMDM Disease mutations80145
Blocks (Seattle)THOC7
SuperfamilyQ6I9Y2
Human Protein Atlas [tissue]ENSG00000163634-THOC7 [tissue]
Peptide AtlasQ6I9Y2
HPRD17632
IPIIPI00291131   IPI00946797   IPI00945932   IPI00789090   
Protein Interaction databases
DIP (DOE-UCLA)Q6I9Y2
IntAct (EBI)Q6I9Y2
FunCoupENSG00000163634
BioGRIDTHOC7
STRING (EMBL)THOC7
ZODIACTHOC7
Ontologies - Pathways
QuickGOQ6I9Y2
Ontology : AmiGOtranscription export complex  THO complex  THO complex part of transcription export complex  THO complex part of transcription export complex  nuclear chromosome, telomeric region  RNA binding  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  RNA export from nucleus  mRNA export from nucleus  mRNA export from nucleus  mRNA export from nucleus  RNA splicing  nuclear speck  mRNA 3'-end processing  viral mRNA export from host cell nucleus  
Ontology : EGO-EBItranscription export complex  THO complex  THO complex part of transcription export complex  THO complex part of transcription export complex  nuclear chromosome, telomeric region  RNA binding  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  RNA export from nucleus  mRNA export from nucleus  mRNA export from nucleus  mRNA export from nucleus  RNA splicing  nuclear speck  mRNA 3'-end processing  viral mRNA export from host cell nucleus  
NDEx NetworkTHOC7
Atlas of Cancer Signalling NetworkTHOC7
Wikipedia pathwaysTHOC7
Orthology - Evolution
OrthoDB80145
GeneTree (enSembl)ENSG00000163634
Phylogenetic Trees/Animal Genes : TreeFamTHOC7
HOGENOMQ6I9Y2
Homologs : HomoloGeneTHOC7
Homology/Alignments : Family Browser (UCSC)THOC7
Gene fusions - Rearrangements
Fusion : QuiverTHOC7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTHOC7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)THOC7
dbVarTHOC7
ClinVarTHOC7
1000_GenomesTHOC7 
Exome Variant ServerTHOC7
GNOMAD BrowserENSG00000163634
Varsome BrowserTHOC7
Genetic variants : HAPMAP80145
Genomic Variants (DGV)THOC7 [DGVbeta]
DECIPHERTHOC7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTHOC7 
Mutations
ICGC Data PortalTHOC7 
TCGA Data PortalTHOC7 
Broad Tumor PortalTHOC7
OASIS PortalTHOC7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTHOC7  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTHOC7
Mutations and Diseases : HGMDTHOC7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch THOC7
DgiDB (Drug Gene Interaction Database)THOC7
DoCM (Curated mutations)THOC7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)THOC7 (select a term)
intoGenTHOC7
Cancer3DTHOC7(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611965   
Orphanet
DisGeNETTHOC7
MedgenTHOC7
Genetic Testing Registry THOC7
NextProtQ6I9Y2 [Medical]
TSGene80145
GENETestsTHOC7
Target ValidationTHOC7
Huge Navigator THOC7 [HugePedia]
snp3D : Map Gene to Disease80145
BioCentury BCIQTHOC7
ClinGenTHOC7
Clinical trials, drugs, therapy
Protein Interactions : CTD80145
Pharm GKB GenePA144596266
Clinical trialTHOC7
Miscellaneous
canSAR (ICR)THOC7 (select the gene name)
HarmonizomeTHOC7
DataMed IndexTHOC7
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTHOC7
EVEXTHOC7
GoPubMedTHOC7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 16:32:36 CEST 2020
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