Identity
HGNC
LOCATION
3q27.1
LOCUSID
ALIAS
MGDF,MKCSF,ML,MPLLG,THCYT1,TPO
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7066
MIM: 600044
HGNC: 11795
Ensembl: ENSG00000090534
Variants:
dbSNP: 7066
ClinVar: 7066
TCGA: ENSG00000090534
COSMIC: THPO
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37962621 | 2024 | Hereditary thrombocythemia due to splicing donor site mutation of THPO in a Japanese family. | 0 |
| 37962621 | 2024 | Hereditary thrombocythemia due to splicing donor site mutation of THPO in a Japanese family. | 0 |
| 36226497 | 2023 | Defective binding of ETS1 and STAT4 due to a mutation in the promoter region of THPO as a novel mechanism of congenital amegakaryocytic thrombocytopenia. | 1 |
| 36226497 | 2023 | Defective binding of ETS1 and STAT4 due to a mutation in the promoter region of THPO as a novel mechanism of congenital amegakaryocytic thrombocytopenia. | 1 |
| 36534659 | 2022 | Novel THPO variant in hereditary thrombocytopenia: A potential candidate variant for predisposition to myeloid neoplasm. | 0 |
| 36534659 | 2022 | Novel THPO variant in hereditary thrombocytopenia: A potential candidate variant for predisposition to myeloid neoplasm. | 0 |
| 33238000 | 2021 | Increased B4GALT1 expression is associated with platelet surface galactosylation and thrombopoietin plasma levels in MPNs. | 8 |
| 33673041 | 2021 | Cooperative Role of Thrombopoietin and Vascular Endothelial Growth Factor-A in the Progression of Liver Cirrhosis to Hepatocellular Carcinoma. | 5 |
| 34247039 | 2021 | Clinical applications of thrombopoietin silencing: A possible therapeutic role in COVID-19? | 1 |
| 33238000 | 2021 | Increased B4GALT1 expression is associated with platelet surface galactosylation and thrombopoietin plasma levels in MPNs. | 8 |
| 33673041 | 2021 | Cooperative Role of Thrombopoietin and Vascular Endothelial Growth Factor-A in the Progression of Liver Cirrhosis to Hepatocellular Carcinoma. | 5 |
| 34247039 | 2021 | Clinical applications of thrombopoietin silencing: A possible therapeutic role in COVID-19? | 1 |
| 32150607 | 2020 | Monoallelic loss-of-function THPO variants cause heritable thrombocytopenia. | 7 |
| 32337844 | 2020 | Endogenous thrombopoietin promotes non-small-cell lung carcinoma cell proliferation and migration by regulating EGFR signalling. | 4 |
| 32341206 | 2020 | c-Mpl and TPO expression in the human central nervous system neurons inhibits neuronal apoptosis. | 4 |
Citation
Dessen P
THPO (thrombopoietin)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42552/thpo
