Identity
HGNC
LOCATION
13q14.3
LOCUSID
ALIAS
ANIB12,TMTSP,UNQ3010
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55901
MIM: 616821
HGNC: 17754
Ensembl: ENSG00000136114
Variants:
dbSNP: 55901
ClinVar: 55901
TCGA: ENSG00000136114
COSMIC: THSD1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000136114 | ENST00000258613 | Q9NS62 |
| ENSG00000136114 | ENST00000258613 | A0A024R064 |
| ENSG00000136114 | ENST00000349258 | Q9NS62 |
| ENSG00000136114 | ENST00000648254 | Q9NS62 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38396816 | 2024 | THSD1 Suppresses Autophagy-Mediated Focal Adhesion Turnover by Modulating the FAK-Beclin 1 Pathway. | 0 |
| 38396816 | 2024 | THSD1 Suppresses Autophagy-Mediated Focal Adhesion Turnover by Modulating the FAK-Beclin 1 Pathway. | 0 |
| 33569873 | 2021 | Manifestations of thrombospondin type-1 domain-containing protein 1 gene mutation in an extremely premature infant with nonimmune hydrops fetalis. | 0 |
| 33569873 | 2021 | Manifestations of thrombospondin type-1 domain-containing protein 1 gene mutation in an extremely premature infant with nonimmune hydrops fetalis. | 0 |
| 30055085 | 2018 | A recessive truncating variant in thrombospondin-1 domain containing protein 1 gene THSD1 is the underlying cause of nonimmune hydrops fetalis, congenital cardiac defects, and haemangiomas in four patients from a consanguineous family. | 4 |
| 30055085 | 2018 | A recessive truncating variant in thrombospondin-1 domain containing protein 1 gene THSD1 is the underlying cause of nonimmune hydrops fetalis, congenital cardiac defects, and haemangiomas in four patients from a consanguineous family. | 4 |
| 29069646 | 2017 | The Intracranial Aneurysm Gene THSD1 Connects Endosome Dynamics to Nascent Focal Adhesion Assembly. | 7 |
| 29069646 | 2017 | The Intracranial Aneurysm Gene THSD1 Connects Endosome Dynamics to Nascent Focal Adhesion Assembly. | 7 |
| 26822228 | 2016 | THSD1 preserves vascular integrity and protects against intraplaque haemorrhaging in ApoE-/- mice. | 17 |
| 27895300 | 2016 | THSD1 (Thrombospondin Type 1 Domain Containing Protein 1) Mutation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage. | 24 |
| 26822228 | 2016 | THSD1 preserves vascular integrity and protects against intraplaque haemorrhaging in ApoE-/- mice. | 17 |
| 27895300 | 2016 | THSD1 (Thrombospondin Type 1 Domain Containing Protein 1) Mutation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage. | 24 |
| 22664866 | 2012 | Genome-wide screening for methylation-silenced genes in colorectal cancer. | 11 |
| 22664866 | 2012 | Genome-wide screening for methylation-silenced genes in colorectal cancer. | 11 |
| 18403638 | 2008 | Monochromosome transfer and microarray analysis identify a critical tumor-suppressive region mapping to chromosome 13q14 and THSD1 in esophageal carcinoma. | 10 |
Citation
Dessen P
THSD1 (thrombospondin type 1 domain containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-08-01
Online version: http://atlasgeneticsoncology.org/gene/50286/thsd1
