Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 201633
MIM: 612859
HGNC: 26838
Ensembl: ENSG00000181847
Variants:
dbSNP: 201633
ClinVar: 201633
TCGA: ENSG00000181847
COSMIC: TIGIT
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cell adhesion molecules (CAMs) | KEGG | ko04514 |
| Cell adhesion molecules (CAMs) | KEGG | hsa04514 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37749409 | 2024 | Decreased expression of TIGIT on CD14 + monocytes correlates with clinical features and laboratory parameters of patients with primary Sjögren's syndrome. | 1 |
| 37952520 | 2024 | LAG3 and TIGIT Expression on Tumor-Infiltrating Lymphocytes in Cutaneous Melanoma. | 1 |
| 38216949 | 2024 | The immune checkpoint TIGIT/CD155 promotes the exhaustion of CD8 + T cells in TNBC through glucose metabolic reprogramming mediated by PI3K/AKT/mTOR signaling. | 0 |
| 38305286 | 2024 | Ectopic Expression of TIGIT in Lung Adenocarcinoma and Its Clinical Significance. | 0 |
| 38427556 | 2024 | Combining TIGIT Blockade with MDSC Inhibition Hinders Breast Cancer Bone Metastasis by Activating Antitumor Immunity. | 1 |
| 38461541 | 2024 | FCRL3 expression is upregulated and closely correlates with TIGIT expression in regulatory T cells of patients with systemic lupus erythematosus. | 0 |
| 38852289 | 2024 | Targeting the dynamic transcriptional landscape of Treg subpopulations in pancreatic ductal adenocarcinoma: Insights from single-cell RNA sequencing analysis with a focus on CTLA4 and TIGIT. | 0 |
| 38868776 | 2024 | TIGIT(+)Tfh show poor B-helper function and negatively correlate with SARS-CoV-2 antibody titre. | 0 |
| 37749409 | 2024 | Decreased expression of TIGIT on CD14 + monocytes correlates with clinical features and laboratory parameters of patients with primary Sjögren's syndrome. | 1 |
| 37952520 | 2024 | LAG3 and TIGIT Expression on Tumor-Infiltrating Lymphocytes in Cutaneous Melanoma. | 1 |
| 38216949 | 2024 | The immune checkpoint TIGIT/CD155 promotes the exhaustion of CD8 + T cells in TNBC through glucose metabolic reprogramming mediated by PI3K/AKT/mTOR signaling. | 0 |
| 38305286 | 2024 | Ectopic Expression of TIGIT in Lung Adenocarcinoma and Its Clinical Significance. | 0 |
| 38427556 | 2024 | Combining TIGIT Blockade with MDSC Inhibition Hinders Breast Cancer Bone Metastasis by Activating Antitumor Immunity. | 1 |
| 38461541 | 2024 | FCRL3 expression is upregulated and closely correlates with TIGIT expression in regulatory T cells of patients with systemic lupus erythematosus. | 0 |
| 38852289 | 2024 | Targeting the dynamic transcriptional landscape of Treg subpopulations in pancreatic ductal adenocarcinoma: Insights from single-cell RNA sequencing analysis with a focus on CTLA4 and TIGIT. | 0 |
Citation
Dessen P
TIGIT (T cell immunoreceptor with Ig and ITIM domains)
Atlas Genet Cytogenet Oncol Haematol. 2010-01-01
Online version: http://atlasgeneticsoncology.org/gene/51271/tigit
