Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7082
MIM: 601009
HGNC: 11827
Ensembl: ENSG00000104067
Variants:
dbSNP: 7082
ClinVar: 7082
TCGA: ENSG00000104067
COSMIC: TJP1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447216 | Schizophrenia | Disease | ClinicalAnnotation | associated | PD | ||
| PA451257 | risperidone | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38630149 | 2024 | circRNA-PTPN4 mediated regulation of FOXO3 and ZO-1 expression: implications for blood-brain barrier integrity and cognitive function in uremic encephalopathy. | 0 |
| 38795825 | 2024 | TJP1 suppresses trophoblast cell invasion by expressing E2F8 in the human placenta. | 0 |
| 38630149 | 2024 | circRNA-PTPN4 mediated regulation of FOXO3 and ZO-1 expression: implications for blood-brain barrier integrity and cognitive function in uremic encephalopathy. | 0 |
| 38795825 | 2024 | TJP1 suppresses trophoblast cell invasion by expressing E2F8 in the human placenta. | 0 |
| 36719664 | 2023 | ZO-1 expression in normal human macula densa: Immunohistochemical and immunofluorescence investigations. | 1 |
| 36768287 | 2023 | Does the Blood-Brain Barrier Integrity Change in Regard to the Onset of Fetal Growth Restriction? | 1 |
| 36897043 | 2023 | Rabeprazole destroyed gastric epithelial barrier function through FOXF1/STAT3-mediated ZO-1 expression. | 0 |
| 36929868 | 2023 | Hypoxic nasopharyngeal carcinoma-derived exosomal miR-455 increases vascular permeability by targeting ZO-1 to promote metastasis. | 4 |
| 36946050 | 2023 | [Porphyromonas gingivalis infection causes umbilical vein endothelial barrier dysfunction in vitro by down-regulating ZO-1, occludin and VE-cadherin expression]. | 1 |
| 37354899 | 2023 | Loss of TJP1 disrupts gastrulation patterning and increases differentiation toward the germ cell lineage in human pluripotent stem cells. | 5 |
| 37852424 | 2023 | CLDN6 inhibits colorectal cancer proliferation dependent on restraining p53 ubiquitination via ZO-1/PTEN axis. | 1 |
| 36719664 | 2023 | ZO-1 expression in normal human macula densa: Immunohistochemical and immunofluorescence investigations. | 1 |
| 36768287 | 2023 | Does the Blood-Brain Barrier Integrity Change in Regard to the Onset of Fetal Growth Restriction? | 1 |
| 36897043 | 2023 | Rabeprazole destroyed gastric epithelial barrier function through FOXF1/STAT3-mediated ZO-1 expression. | 0 |
| 36929868 | 2023 | Hypoxic nasopharyngeal carcinoma-derived exosomal miR-455 increases vascular permeability by targeting ZO-1 to promote metastasis. | 4 |
Citation
Dessen P
TJP1 (tight junction protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45883/tjp1
