Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9874
MIM: 608438
HGNC: 11841
Ensembl: ENSG00000198586
Variants:
dbSNP: 9874
ClinVar: 9874
TCGA: ENSG00000198586
COSMIC: TLK1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198586 | ENST00000359766 | F8W7X8 |
| ENSG00000198586 | ENST00000409443 | B3KRP1 |
| ENSG00000198586 | ENST00000431350 | Q9UKI8 |
| ENSG00000198586 | ENST00000453628 | C9JWT6 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38498025 | 2024 | The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1β-mediated AML progression. | 0 |
| 38498025 | 2024 | The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1β-mediated AML progression. | 0 |
| 36947060 | 2023 | The interaction between ASF1B and TLK1 promotes the malignant progression of low-grade glioma. | 2 |
| 37462140 | 2023 | CircTLK1 alleviates oxygen-glucose deprivation/reperfusion induced apoptosis in HK-2 cells through miR-136-5p/Bcl2 signal axis. | 1 |
| 37686173 | 2023 | Untousling the Role of Tousled-like Kinase 1 in DNA Damage Repair. | 2 |
| 36947060 | 2023 | The interaction between ASF1B and TLK1 promotes the malignant progression of low-grade glioma. | 2 |
| 37462140 | 2023 | CircTLK1 alleviates oxygen-glucose deprivation/reperfusion induced apoptosis in HK-2 cells through miR-136-5p/Bcl2 signal axis. | 1 |
| 37686173 | 2023 | Untousling the Role of Tousled-like Kinase 1 in DNA Damage Repair. | 2 |
| 34731387 | 2022 | CircTLK1 Downregulation Attenuates High Glucose-Induced Human Mesangial Cell Injury by Blocking the AKT/NF-κB Pathway Through Sponging miR-126-5p/miR-204-5p. | 7 |
| 35064619 | 2022 | TLK1-mediated MK5-S354 phosphorylation drives prostate cancer cell motility and may signify distinct pathologies. | 5 |
| 34731387 | 2022 | CircTLK1 Downregulation Attenuates High Glucose-Induced Human Mesangial Cell Injury by Blocking the AKT/NF-κB Pathway Through Sponging miR-126-5p/miR-204-5p. | 7 |
| 35064619 | 2022 | TLK1-mediated MK5-S354 phosphorylation drives prostate cancer cell motility and may signify distinct pathologies. | 5 |
| 34410682 | 2021 | CircTLK1 modulates sepsis-induced cardiomyocyte apoptosis via enhancing PARP1/HMGB1 axis-mediated mitochondrial DNA damage by sponging miR-17-5p. | 14 |
| 34410682 | 2021 | CircTLK1 modulates sepsis-induced cardiomyocyte apoptosis via enhancing PARP1/HMGB1 axis-mediated mitochondrial DNA damage by sponging miR-17-5p. | 14 |
| 31362519 | 2020 | Variation analysis of tousled like kinase 1 gene in patients with sporadic premature ovarian insufficiency. | 0 |
Citation
Dessen P
TLK1 (tousled like kinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43529/tlk1
