Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 83660
MIM: 607349
HGNC: 15447
Ensembl: ENSG00000171914
Variants:
dbSNP: 83660
ClinVar: 83660
TCGA: ENSG00000171914
COSMIC: TLN2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000171914 | ENST00000472902 | H0YN01 |
| ENSG00000171914 | ENST00000494733 | H0YMT1 |
| ENSG00000171914 | ENST00000561311 | Q9Y4G6 |
| ENSG00000171914 | ENST00000636159 | A0A1B0GVU7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37460977 | 2023 | Talin2 and KANK2 functionally interact to regulate microtubule dynamics, paclitaxel sensitivity and cell migration in the MDA-MB-435S melanoma cell line. | 1 |
| 37460977 | 2023 | Talin2 and KANK2 functionally interact to regulate microtubule dynamics, paclitaxel sensitivity and cell migration in the MDA-MB-435S melanoma cell line. | 1 |
| 36329586 | 2022 | [Expression of miR-4324 and its targeted gene Talin2 in breast cancer]. | 0 |
| 36329586 | 2022 | [Expression of miR-4324 and its targeted gene Talin2 in breast cancer]. | 0 |
| 32198023 | 2020 | Talin2 mediates secretion and trafficking of matrix metallopeptidase 9 during invadopodium formation. | 3 |
| 32605925 | 2020 | A distinct talin2 structure directs isoform specificity in cell adhesion. | 8 |
| 32657269 | 2020 | Phosphoinositides regulate force-independent interactions between talin, vinculin, and actin. | 28 |
| 32198023 | 2020 | Talin2 mediates secretion and trafficking of matrix metallopeptidase 9 during invadopodium formation. | 3 |
| 32605925 | 2020 | A distinct talin2 structure directs isoform specificity in cell adhesion. | 8 |
| 32657269 | 2020 | Phosphoinositides regulate force-independent interactions between talin, vinculin, and actin. | 28 |
| 30201328 | 2018 | Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease. | 17 |
| 30201328 | 2018 | Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease. | 17 |
| 26822056 | 2016 | Both Talin-1 and Talin-2 correlate with malignancy potential of the human hepatocellular carcinoma MHCC-97 L cell. | 26 |
| 27223613 | 2016 | Exome Sequencing of a Pedigree Reveals S339L Mutation in the TLN2 Gene as a Cause of Fifth Finger Camptodactyly. | 8 |
| 27694340 | 2016 | Talin2-mediated traction force drives matrix degradation and cell invasion. | 24 |
Citation
Dessen P
TLN2 (talin 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-05-01
Online version: http://atlasgeneticsoncology.org/gene/47537/tln2
