Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64114
MIM: 610364
HGNC: 23410
Ensembl: ENSG00000135926
Variants:
dbSNP: 64114
ClinVar: 64114
TCGA: ENSG00000135926
COSMIC: TMBIM1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37823951 | 2024 | MicroRNA-582-3p knockdown alleviates non-alcoholic steatohepatitis by altering the gut microbiota composition and moderating TMBIM1. | 1 |
| 37823951 | 2024 | MicroRNA-582-3p knockdown alleviates non-alcoholic steatohepatitis by altering the gut microbiota composition and moderating TMBIM1. | 1 |
| 34099068 | 2021 | Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences. | 7 |
| 34099068 | 2021 | Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences. | 7 |
| 30447906 | 2019 | Genetic variant of TMBIM1 is associated with the susceptibility of colorectal cancer in the Chinese population. | 3 |
| 30447906 | 2019 | Genetic variant of TMBIM1 is associated with the susceptibility of colorectal cancer in the Chinese population. | 3 |
| 28481357 | 2017 | Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4. | 48 |
| 28481357 | 2017 | Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4. | 48 |
| 27005424 | 2016 | Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease. | 26 |
| 27005424 | 2016 | Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease. | 26 |
| 25764978 | 2015 | The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA²⁺-filling state. | 40 |
| 25764978 | 2015 | The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA²⁺-filling state. | 40 |
| 21107705 | 2011 | A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface. | 0 |
| 21107705 | 2011 | A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface. | 0 |
| 18440869 | 2008 | Comparative genomics and function analysis on BI1 family. | 10 |
Citation
Dessen P
TMBIM1 (transmembrane BAX inhibitor motif containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-11-01
Online version: http://atlasgeneticsoncology.org/gene/51179/tmbim1
