Identity
HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
EV2,EVER2,EVIN2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 147138
MIM: 605829
HGNC: 20474
Ensembl: ENSG00000167895
Variants:
dbSNP: 147138
ClinVar: 147138
TCGA: ENSG00000167895
COSMIC: TMC8
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000167895 | ENST00000318430 | Q8IU68 |
| ENSG00000167895 | ENST00000318430 | A0A024R8N8 |
| ENSG00000167895 | ENST00000589691 | Q8IU68 |
| ENSG00000167895 | ENST00000590799 | K7EJ72 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36170758 | 2022 | Establishment of a human induced pluripotent stem cell line, KMUGMCi005-A, from a patient with Epidermodysplasia verruciformis (EV) bearing homozygous splicing donor site mutation in the TMC8 gene. | 0 |
| 36170758 | 2022 | Establishment of a human induced pluripotent stem cell line, KMUGMCi005-A, from a patient with Epidermodysplasia verruciformis (EV) bearing homozygous splicing donor site mutation in the TMC8 gene. | 0 |
| 34459021 | 2021 | Case of epidermodysplasia verruciformis with a novel mutation of TMC8. | 1 |
| 34459021 | 2021 | Case of epidermodysplasia verruciformis with a novel mutation of TMC8. | 1 |
| 32917726 | 2020 | Expression of a TMC6-TMC8-CIB1 heterotrimeric complex in lymphocytes is regulated by each of the components. | 4 |
| 32917726 | 2020 | Expression of a TMC6-TMC8-CIB1 heterotrimeric complex in lymphocytes is regulated by each of the components. | 4 |
| 30068544 | 2018 | The human CIB1-EVER1-EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses. | 60 |
| 30068544 | 2018 | The human CIB1-EVER1-EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses. | 60 |
| 28646613 | 2017 | Novel TMC8 splice site mutation in epidermodysplasia verruciformis and review of HPV infections in patients with the disease. | 11 |
| 28646613 | 2017 | Novel TMC8 splice site mutation in epidermodysplasia verruciformis and review of HPV infections in patients with the disease. | 11 |
| 27097911 | 2016 | Variants of EVER1 and EVER2 (TMC6 and TMC8) and human papillomavirus status in patients with mucosal squamous cell carcinoma of the head and neck. | 9 |
| 27899077 | 2016 | Genetic polymorphisms of FAS and EVER genes in a Greek population and their susceptibility to cervical cancer: a case control study. | 3 |
| 27097911 | 2016 | Variants of EVER1 and EVER2 (TMC6 and TMC8) and human papillomavirus status in patients with mucosal squamous cell carcinoma of the head and neck. | 9 |
| 27899077 | 2016 | Genetic polymorphisms of FAS and EVER genes in a Greek population and their susceptibility to cervical cancer: a case control study. | 3 |
| 23534907 | 2015 | Epidermodysplasia verruciformis in lipoid proteinosis: case report and discussion of pathophysiology. | 1 |
Citation
Dessen P
TMC8 (transmembrane channel like 8)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40508/tmc8
