| Nomenclature |
|---|
| HGNC (Hugo) | TMED10 16998 |
| Cards |
|---|
| Entrez_Gene (NCBI) | TMED10 10972 transmembrane p24 trafficking protein 10 |
| Aliases | P24(DELTA); S31I125; S31III125; TMP21; |
| Tmp-21-I; p23; p24d1 |
| GeneCards (Weizmann) | TMED10 |
| Ensembl hg19 (Hinxton) | ENSG00000170348 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000170348 [Gene_View] ENSG00000170348 [Sequence] chr14:75131469-75176612 [Contig_View] TMED10 [Vega] |
| ICGC DataPortal | ENSG00000170348 |
| TCGA cBioPortal | TMED10 |
| AceView (NCBI) | TMED10 |
| Genatlas (Paris) | TMED10 |
| WikiGenes | 10972 |
| SOURCE (Princeton) | TMED10 |
| Genetics Home Reference (NIH) | TMED10 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | TMED10 - chr14:75131469-75176612 - 14q24.3 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | TMED10 - 14q24.3 [Description] (hg19-Feb_2009) |
| GoldenPath | TMED10 - 14q24.3 [CytoView hg19] TMED10 - 14q24.3 [CytoView hg38] |
| Genome Data Viewer NCBI | TMED10 [Mapview hg19] |
| OMIM | 605406 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AJ004913 AK023615 AK056156 AK222972 AK296800 |
| RefSeq transcript (Entrez) | NM_006827 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | TMED10 |
| Alternative Splicing Gallery | ENSG00000170348 |
| Gene Expression | TMED10 [ NCBI-GEO ] TMED10 [ EBI - ARRAY_EXPRESS ]
TMED10 [ SEEK ] TMED10 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | TMED10 [ Firebrowse - Broad ] |
| Genevisible | Expression of TMED10 in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 10972 |
| GTEX Portal (Tissue expression) | TMED10 |
| Human Protein Atlas | ENSG00000170348-TMED10 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P49755 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P49755 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P49755 |
| Splice isoforms : SwissVar | P49755 |
| PhosPhoSitePlus | P49755 |
| Domaine pattern : Prosite (Expaxy) | GOLD (PS50866) |
| Domains : Interpro (EBI) | GOLD_dom TMP21-related |
| Domain families : Pfam (Sanger) | EMP24_GP25L (PF01105) |
| Domain families : Pfam (NCBI) | pfam01105 |
| Domain families : Smart (EMBL) | EMP24_GP25L (SM01190) |
| Conserved Domain (NCBI) | TMED10 |
| DMDM Disease mutations | 10972 |
| Superfamily | P49755 |
| Human Protein Atlas [tissue] | ENSG00000170348-TMED10 [tissue] |
| Peptide Atlas | P49755 |
| HPRD | 12013 |
| IPI | IPI00028055 IPI01026466 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P49755 |
| IntAct (EBI) | P49755 |
| FunCoup | ENSG00000170348 |
| BioGRID | TMED10 |
| STRING (EMBL) | TMED10 |
| ZODIAC | TMED10 |
| Ontologies - Pathways |
|---|
| QuickGO | P49755 |
| Ontology : AmiGO | Golgi membrane kidney development protein binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum-Golgi intermediate compartment endoplasmic reticulum-Golgi intermediate compartment Golgi apparatus Golgi apparatus cis-Golgi network plasma membrane intracellular protein transport intracellular protein transport ER to Golgi vesicle-mediated transport ER to Golgi vesicle-mediated transport retrograde vesicle-mediated transport, Golgi to ER retrograde vesicle-mediated transport, Golgi to ER Golgi organization ER to Golgi transport vesicle membrane integral component of membrane syntaxin binding transport vesicle COPII-coated ER to Golgi transport vesicle COPI-coated vesicle COPI-coated vesicle trans-Golgi network transport vesicle secretory granule membrane endoplasmic reticulum-Golgi intermediate compartment membrane cargo loading into vesicle COPI-coated vesicle budding melanosome zymogen granule membrane response to alkaloid protein-containing complex binding regulated exocytosis vesicle targeting, to, from or within Golgi COPI coating of Golgi vesicle COPII vesicle coating gamma-secretase complex regulation of amyloid-beta formation |
| Ontology : EGO-EBI | Golgi membrane kidney development protein binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum-Golgi intermediate compartment endoplasmic reticulum-Golgi intermediate compartment Golgi apparatus Golgi apparatus cis-Golgi network plasma membrane intracellular protein transport intracellular protein transport ER to Golgi vesicle-mediated transport ER to Golgi vesicle-mediated transport retrograde vesicle-mediated transport, Golgi to ER retrograde vesicle-mediated transport, Golgi to ER Golgi organization ER to Golgi transport vesicle membrane integral component of membrane syntaxin binding transport vesicle COPII-coated ER to Golgi transport vesicle COPI-coated vesicle COPI-coated vesicle trans-Golgi network transport vesicle secretory granule membrane endoplasmic reticulum-Golgi intermediate compartment membrane cargo loading into vesicle COPI-coated vesicle budding melanosome zymogen granule membrane response to alkaloid protein-containing complex binding regulated exocytosis vesicle targeting, to, from or within Golgi COPI coating of Golgi vesicle COPII vesicle coating gamma-secretase complex regulation of amyloid-beta formation |
| NDEx Network | TMED10 |
| Atlas of Cancer Signalling Network | TMED10 |
| Wikipedia pathways | TMED10 |
| Orthology - Evolution |
|---|
| OrthoDB | 10972 |
| GeneTree (enSembl) | ENSG00000170348 |
| Phylogenetic Trees/Animal Genes : TreeFam | TMED10 |
| HOGENOM | P49755 |
| Homologs : HomoloGene | TMED10 |
| Homology/Alignments : Family Browser (UCSC) | TMED10 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | TMED10 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | TMED10 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | TMED10 |
| dbVar | TMED10 |
| ClinVar | TMED10 |
| 1000_Genomes | TMED10 |
| Exome Variant Server | TMED10 |
| GNOMAD Browser | ENSG00000170348 |
| Varsome Browser | TMED10 |
| Genetic variants : HAPMAP | 10972 |
| Genomic Variants (DGV) | TMED10 [DGVbeta] |
| DECIPHER | TMED10 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | TMED10 |
| Mutations |
|---|
| ICGC Data Portal | TMED10 |
| TCGA Data Portal | TMED10 |
| Broad Tumor Portal | TMED10 |
| OASIS Portal | TMED10 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | TMED10 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | TMED10 |
| Mutations and Diseases : HGMD | TMED10 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | select TMED10 |
| DgiDB (Drug Gene Interaction Database) | TMED10 |
| DoCM (Curated mutations) | TMED10 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | TMED10 (select a term) |
| intoGen | TMED10 |
| Cancer3D | TMED10 (select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 605406 |
| Orphanet | |
| DisGeNET | TMED10 |
| Medgen | TMED10 |
| Genetic Testing Registry | TMED10
|
| NextProt | P49755 [Medical] |
| TSGene | 10972 |
| GENETests | TMED10 |
| Open Targets Genetics | ENSG00000170348 [validation] |
| snp3D : Map Gene to Disease | 10972 |
| BioCentury BCIQ | TMED10 |
| ClinGen | TMED10 |
| Clinical trials, drugs, therapy |
|---|
| Protein Interactions : CTD | 10972 |
| Pharm GKB Gene | PA128394579 |
| Clinical trial | TMED10 |
| Miscellaneous |
|---|
| canSAR (ICR) | TMED10 (select the gene name) |
| Harmonizome | TMED10 |
| DataMed Index | TMED10 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 93 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | TMED10 |
| EVEX | TMED10 |
