Identity
HGNC
LOCATION
12q24.31
LOCUSID
ALIAS
P24A,RNP24,p24,p24b1,p24beta1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10959
HGNC: 16996
Ensembl: ENSG00000086598
Variants:
dbSNP: 10959
ClinVar: 10959
TCGA: ENSG00000086598
COSMIC: TMED2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000086598 | ENST00000262225 | Q15363 |
| ENSG00000086598 | ENST00000262225 | Q6FHT8 |
| ENSG00000086598 | ENST00000438031 | E7EQ72 |
| ENSG00000086598 | ENST00000509052 | F5GX39 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37391589 | 2023 | VIRMA facilitates intrahepatic cholangiocarcinoma progression through epigenetic augmentation of TMED2 and PARD3B mRNA stabilization. | 1 |
| 37615927 | 2023 | TMED2 Induces Cisplatin Resistance in Breast Cancer via Targeting the KEAP1-Nrf2 Pathway. | 0 |
| 37391589 | 2023 | VIRMA facilitates intrahepatic cholangiocarcinoma progression through epigenetic augmentation of TMED2 and PARD3B mRNA stabilization. | 1 |
| 37615927 | 2023 | TMED2 Induces Cisplatin Resistance in Breast Cancer via Targeting the KEAP1-Nrf2 Pathway. | 0 |
| 35135563 | 2022 | Transmembrane p24 trafficking protein 2 regulates inflammation through the TLR4/NF-κB signaling pathway in lung adenocarcinoma. | 5 |
| 35135563 | 2022 | Transmembrane p24 trafficking protein 2 regulates inflammation through the TLR4/NF-κB signaling pathway in lung adenocarcinoma. | 5 |
| 32293333 | 2020 | The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10. | 8 |
| 32293333 | 2020 | The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10. | 8 |
| 30540941 | 2018 | TMED2 Potentiates Cellular IFN Responses to DNA Viruses by Reinforcing MITA Dimerization and Facilitating Its Trafficking. | 45 |
| 30540941 | 2018 | TMED2 Potentiates Cellular IFN Responses to DNA Viruses by Reinforcing MITA Dimerization and Facilitating Its Trafficking. | 45 |
| 27569046 | 2016 | 3D Structure and Interaction of p24β and p24δ Golgi Dynamics Domains: Implication for p24 Complex Formation and Cargo Transport. | 20 |
| 27569046 | 2016 | 3D Structure and Interaction of p24β and p24δ Golgi Dynamics Domains: Implication for p24 Complex Formation and Cargo Transport. | 20 |
| 22212250 | 2012 | TMED2/p24β1 is expressed in all gestational stages of human placentas and in choriocarcinoma cell lines. | 12 |
| 22212250 | 2012 | TMED2/p24β1 is expressed in all gestational stages of human placentas and in choriocarcinoma cell lines. | 12 |
| 21219331 | 2011 | Proteinase-activated receptors, nucleotide P2Y receptors, and μ-opioid receptor-1B are under the control of the type I transmembrane proteins p23 and p24A in post-Golgi trafficking. | 13 |
Citation
Dessen P
TMED2 (transmembrane p24 trafficking protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2011-07-01
Online version: http://atlasgeneticsoncology.org/gene/52521/tmed2
