TMEFF2 (transmembrane protein with EGF like and two follistatin like domains 2)

2003-02-01  

Identity

HGNC
LOCATION
2q32.3
LOCUSID
ALIAS
CT120.2,HPP1,TENB2,TPEF,TR,TR-2
FUSION GENES

Other Information

Locus ID:

NCBI: 23671
MIM: 605734
HGNC: 11867
Ensembl: ENSG00000144339

Variants:

dbSNP: 23671
ClinVar: 23671
TCGA: ENSG00000144339
COSMIC: TMEFF2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144339ENST00000272771Q9UIK5
ENSG00000144339ENST00000392314Q9UIK5
ENSG00000144339ENST00000409056Q9UIK5

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
343397052021Prognostic and clinicopathological significance of TMEFF2, SMOC-2, and SOX17 expression in endometrial carcinoma.7
343397052021Prognostic and clinicopathological significance of TMEFF2, SMOC-2, and SOX17 expression in endometrial carcinoma.7
316102112020TMEFF2 is a novel prognosis signature and target for endometrial carcinoma.3
320091292020MiR-323-3p Targeting Transmembrane Protein with EGF-Like and 2 Follistatin Domain (TMEFF2) Inhibits Human Lung Cancer A549 Cell Apoptosis by Regulation of AKT and ERK Signaling Pathways.6
324504192020HPP1 Ectodomain Shedding is Mediated by ADAM17 and is Necessary for Tumor Suppression in Colon Cancer.2
324976212020Roles of a TMPO-AS1/microRNA-200c/TMEFF2 ceRNA network in the malignant behaviors and 5-FU resistance of ovarian cancer cells.14
325596212020Long non-coding RNA LINC01963 inhibits progression of pancreatic carcinoma by targeting miR-641/TMEFF2.13
316102112020TMEFF2 is a novel prognosis signature and target for endometrial carcinoma.3
320091292020MiR-323-3p Targeting Transmembrane Protein with EGF-Like and 2 Follistatin Domain (TMEFF2) Inhibits Human Lung Cancer A549 Cell Apoptosis by Regulation of AKT and ERK Signaling Pathways.6
324504192020HPP1 Ectodomain Shedding is Mediated by ADAM17 and is Necessary for Tumor Suppression in Colon Cancer.2
324976212020Roles of a TMPO-AS1/microRNA-200c/TMEFF2 ceRNA network in the malignant behaviors and 5-FU resistance of ovarian cancer cells.14
325596212020Long non-coding RNA LINC01963 inhibits progression of pancreatic carcinoma by targeting miR-641/TMEFF2.13
306147932019Frameshift mutation of candidate tumor suppressor genes QK1 and TMEFF2 in gastric and colorectal cancers.5
310447752019Expression of TMEFF2 in Human Pancreatic Cancer Tissue and the Effects of TMEFF2 Knockdown on Cell, Proliferation, and Apoptosis in Human Pancreatic Cell Lines.1
310605422019A TMEFF2-regulated cell cycle derived gene signature is prognostic of recurrence risk in prostate cancer.6

Citation

Dessen P

TMEFF2 (transmembrane protein with EGF like and two follistatin like domains 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42587/tmeff2