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TMEM121 (transmembrane protein 121)

Identity

Alias_symbol (synonym)MGC4659
hole
Other aliasTMEM121A
HGNC (Hugo) TMEM121
LocusID (NCBI) 80757
Atlas_Id 74784
Location 14q32.33  [Link to chromosome band 14q32]
Location_base_pair Starts at 105526603 and ends at 105530202 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TMEM121 (14q32.33) / ZFC3H1 (12q21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TMEM121   20511
Cards
Entrez_Gene (NCBI)TMEM121  80757  transmembrane protein 121
AliasesTMEM121A; hole
GeneCards (Weizmann)TMEM121
Ensembl hg19 (Hinxton)ENSG00000184986 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184986 [Gene_View]  ENSG00000184986 [Sequence]  chr14:105526603-105530202 [Contig_View]  TMEM121 [Vega]
ICGC DataPortalENSG00000184986
TCGA cBioPortalTMEM121
AceView (NCBI)TMEM121
Genatlas (Paris)TMEM121
WikiGenes80757
SOURCE (Princeton)TMEM121
Genetics Home Reference (NIH)TMEM121
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM121  -     chr14:105526603-105530202 +  14q32.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM121  -     14q32.33   [Description]    (hg19-Feb_2009)
GoldenPathTMEM121 - 14q32.33 [CytoView hg19]  TMEM121 - 14q32.33 [CytoView hg38]
ImmunoBaseENSG00000184986
Mapping of homologs : NCBITMEM121 [Mapview hg19]  TMEM121 [Mapview hg38]
Gene and transcription
Genbank (Entrez)BC004221 HY134492
RefSeq transcript (Entrez)NM_001331238 NM_025268
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM121
Alternative Splicing GalleryENSG00000184986
Gene ExpressionTMEM121 [ NCBI-GEO ]   TMEM121 [ EBI - ARRAY_EXPRESS ]   TMEM121 [ SEEK ]   TMEM121 [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM121 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80757
GTEX Portal (Tissue expression)TMEM121
Human Protein AtlasENSG00000184986-TMEM121 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BTD3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BTD3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BTD3
Splice isoforms : SwissVarQ9BTD3
PhosPhoSitePlusQ9BTD3
Domains : Interpro (EBI)CECR6/TMEM121    TMEM121   
Domain families : Pfam (Sanger)CECR6_TMEM121 (PF14997)   
Domain families : Pfam (NCBI)pfam14997   
Conserved Domain (NCBI)TMEM121
DMDM Disease mutations80757
Blocks (Seattle)TMEM121
SuperfamilyQ9BTD3
Human Protein Atlas [tissue]ENSG00000184986-TMEM121 [tissue]
Peptide AtlasQ9BTD3
HPRD14652
IPIIPI00019336   
Protein Interaction databases
DIP (DOE-UCLA)Q9BTD3
IntAct (EBI)Q9BTD3
FunCoupENSG00000184986
BioGRIDTMEM121
STRING (EMBL)TMEM121
ZODIACTMEM121
Ontologies - Pathways
QuickGOQ9BTD3
Ontology : AmiGOmolecular_function  cellular_component  biological_process  integral component of membrane  
Ontology : EGO-EBImolecular_function  cellular_component  biological_process  integral component of membrane  
NDEx NetworkTMEM121
Atlas of Cancer Signalling NetworkTMEM121
Wikipedia pathwaysTMEM121
Orthology - Evolution
OrthoDB80757
GeneTree (enSembl)ENSG00000184986
Phylogenetic Trees/Animal Genes : TreeFamTMEM121
HOGENOMQ9BTD3
Homologs : HomoloGeneTMEM121
Homology/Alignments : Family Browser (UCSC)TMEM121
Gene fusions - Rearrangements
Fusion : QuiverTMEM121
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM121 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM121
dbVarTMEM121
ClinVarTMEM121
1000_GenomesTMEM121 
Exome Variant ServerTMEM121
ExAC (Exome Aggregation Consortium)ENSG00000184986
GNOMAD BrowserENSG00000184986
Varsome BrowserTMEM121
Genetic variants : HAPMAP80757
Genomic Variants (DGV)TMEM121 [DGVbeta]
DECIPHERTMEM121 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM121 
Mutations
ICGC Data PortalTMEM121 
TCGA Data PortalTMEM121 
Broad Tumor PortalTMEM121
OASIS PortalTMEM121 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM121  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMEM121
Mutations and Diseases : HGMDTMEM121
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TMEM121
DgiDB (Drug Gene Interaction Database)TMEM121
DoCM (Curated mutations)TMEM121 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM121 (select a term)
intoGenTMEM121
Cancer3DTMEM121(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTMEM121
MedgenTMEM121
Genetic Testing Registry TMEM121
NextProtQ9BTD3 [Medical]
TSGene80757
GENETestsTMEM121
Target ValidationTMEM121
Huge Navigator TMEM121 [HugePedia]
snp3D : Map Gene to Disease80757
BioCentury BCIQTMEM121
ClinGenTMEM121
Clinical trials, drugs, therapy
Protein Interactions : CTD80757
Pharm GKB GenePA143485641
Clinical trialTMEM121
Miscellaneous
canSAR (ICR)TMEM121 (select the gene name)
HarmonizomeTMEM121
DataMed IndexTMEM121
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM121
EVEXTMEM121
GoPubMedTMEM121
iHOPTMEM121
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Jun 30 20:04:34 CEST 2020
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