Identity
HGNC
LOCATION
7q36.1
LOCUSID
ALIAS
GS188,HCA112,MS4B1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55365
MIM: 610334
HGNC: 24930
Ensembl: ENSG00000002933
Variants:
dbSNP: 55365
ClinVar: 55365
TCGA: ENSG00000002933
COSMIC: TMEM176A
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34558311 | 2021 | Methylation of TMEM176A, a key ERK signaling regulator, is a novel synthetic lethality marker of ATM inhibitors in human lung cancer. | 6 |
| 34558311 | 2021 | Methylation of TMEM176A, a key ERK signaling regulator, is a novel synthetic lethality marker of ATM inhibitors in human lung cancer. | 6 |
| 31354034 | 2020 | TMEM176A and TMEM176B Are Candidate Regulators of Inhibition of Dendritic Cell Maturation and Function after Chronic Spinal Cord Injury. | 20 |
| 33593482 | 2020 | TMEM176A acts as a tumor suppressor gene in pancreatic cancer by inhibiting ERK signaling. | 6 |
| 31354034 | 2020 | TMEM176A and TMEM176B Are Candidate Regulators of Inhibition of Dendritic Cell Maturation and Function after Chronic Spinal Cord Injury. | 20 |
| 33593482 | 2020 | TMEM176A acts as a tumor suppressor gene in pancreatic cancer by inhibiting ERK signaling. | 6 |
| 30400968 | 2018 | Epigenetic silencing of TMEM176A activates ERK signaling in human hepatocellular carcinoma. | 14 |
| 30400968 | 2018 | Epigenetic silencing of TMEM176A activates ERK signaling in human hepatocellular carcinoma. | 14 |
| 28678648 | 2017 | Methylation of TMEM176A is an independent prognostic marker and is involved in human colorectal cancer development. | 17 |
| 28902459 | 2017 | Exome sequences of multiplex, multigenerational families reveal schizophrenia risk loci with potential implications for neurocognitive performance. | 3 |
| 28678648 | 2017 | Methylation of TMEM176A is an independent prognostic marker and is involved in human colorectal cancer development. | 17 |
| 28902459 | 2017 | Exome sequences of multiplex, multigenerational families reveal schizophrenia risk loci with potential implications for neurocognitive performance. | 3 |
| 27009467 | 2016 | RORγt+ cells selectively express redundant cation channels linked to the Golgi apparatus. | 22 |
| 27009467 | 2016 | RORγt+ cells selectively express redundant cation channels linked to the Golgi apparatus. | 22 |
| 22244448 | 2012 | Abnormal accumulation of human transmembrane (TMEM)-176A and 176B proteins is associated with cancer pathology. | 47 |
Citation
Dessen P
TMEM176A (transmembrane protein 176A)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/40792/tmem176a
