TMEM196 (transmembrane protein 196)

2016-08-01 Affiliation

Identity

HGNC

TMEM196

LOCATION

7p21.1

LOCUSID

256130

ALIAS

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 256130
HGNC: 22431
Ensembl: ENSG00000173452

Variants:

dbSNP: 256130
ClinVar: 256130
TCGA: ENSG00000173452
COSMIC: TMEM196

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000173452	ENST00000405764	Q5HYL7
ENSG00000173452	ENST00000405844	B7WNR7
ENSG00000173452	ENST00000422233	F8WE15
ENSG00000173452	ENST00000433641	Q5HYL7
ENSG00000173452	ENST00000493519	Q5HYL7
ENSG00000173452	ENST00000493519	A0A024RA01

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title
26056045	2015	TMEM196 acts as a novel functional tumour suppressor inactivated by DNA methylation and is a potential prognostic biomarker in lung cancer.
30536447	2019	TMEM196 hypermethylation as a novel diagnostic and prognostic biomarker for lung cancer.
30694883	2019	Associations between TMEM196 polymorphisms and NSAID-exacerbated respiratory disease in asthma.

Citation

Dessen P

TMEM196 (transmembrane protein 196)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55826/tmem196