TMEM45A (transmembrane protein 45A)

2013-06-01  

Identity

HGNC
LOCATION
3q12.2
LOCUSID
ALIAS
DERP7,DNAPTP4
FUSION GENES

Other Information

Locus ID:

NCBI: 55076
MIM: 616928
HGNC: 25480
Ensembl: ENSG00000181458

Variants:

dbSNP: 55076
ClinVar: 55076
TCGA: ENSG00000181458
COSMIC: TMEM45A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181458ENST00000323523Q9NWC5
ENSG00000181458ENST00000403410J3KQ06
ENSG00000181458ENST00000449609C9J9Z5

Expression (GTEx)

0
100
200
300
400
500
600

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
229541402012TMEM45A is essential for hypoxia-induced chemoresistance in breast and liver cancer cells.25
258727852015Inhibition of TMEM45A suppresses proliferation, induces cell cycle arrest and reduces cell invasion in human ovarian cancer cells.14
246893422014High TMEM45A expression is correlated to epidermal keratinization.10
267224552015Knockdown of TMEM45A inhibits the proliferation, migration and invasion of glioma cells.8

Citation

Dessen P

TMEM45A (transmembrane protein 45A)

Atlas Genet Cytogenet Oncol Haematol. 2013-06-01

Online version: http://atlasgeneticsoncology.org/gene/53361/tmem45a