Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TMEM45B (transmembrane protein 45B)

Identity

Alias (NCBI)-
HGNC (Hugo) TMEM45B
HGNC Alias symbBC016153
FLJ40787
LocusID (NCBI) 120224
Atlas_Id 56886
Location 11q24.3  [Link to chromosome band 11q24]
Location_base_pair Starts at 129815848 and ends at 129860003 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FRMD4A (10p13) / TMEM45B (11q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(10;11)(p13;q24) FRMD4A/TMEM45B

External links

Nomenclature
HGNC (Hugo)TMEM45B   25194
Cards
Entrez_Gene (NCBI)TMEM45B  120224  transmembrane protein 45B
Aliases
GeneCards (Weizmann)TMEM45B
Ensembl hg19 (Hinxton)ENSG00000151715 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151715 [Gene_View]  ENSG00000151715 [Sequence]  chr11:129815848-129860003 [Contig_View]  TMEM45B [Vega]
ICGC DataPortalENSG00000151715
TCGA cBioPortalTMEM45B
AceView (NCBI)TMEM45B
Genatlas (Paris)TMEM45B
WikiGenes120224
SOURCE (Princeton)TMEM45B
Genetics Home Reference (NIH)TMEM45B
Genomic and cartography
GoldenPath hg38 (UCSC)TMEM45B  -     chr11:129815848-129860003 +  11q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TMEM45B  -     11q24.3   [Description]    (hg19-Feb_2009)
GoldenPathTMEM45B - 11q24.3 [CytoView hg19]  TMEM45B - 11q24.3 [CytoView hg38]
ImmunoBaseENSG00000151715
genome Data Viewer NCBITMEM45B [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK098106 AK290283 AK292058 BC016153 BM762740
RefSeq transcript (Entrez)NM_001331210 NM_001331211 NM_001331212 NM_138788
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TMEM45B
Alternative Splicing GalleryENSG00000151715
Gene ExpressionTMEM45B [ NCBI-GEO ]   TMEM45B [ EBI - ARRAY_EXPRESS ]   TMEM45B [ SEEK ]   TMEM45B [ MEM ]
Gene Expression Viewer (FireBrowse)TMEM45B [ Firebrowse - Broad ]
GenevisibleExpression of TMEM45B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)120224
GTEX Portal (Tissue expression)TMEM45B
Human Protein AtlasENSG00000151715-TMEM45B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96B21   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96B21  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96B21
Splice isoforms : SwissVarQ96B21
PhosPhoSitePlusQ96B21
Domains : Interpro (EBI)DUF716    TMEM45   
Domain families : Pfam (Sanger)DUF716 (PF04819)   
Domain families : Pfam (NCBI)pfam04819   
Conserved Domain (NCBI)TMEM45B
DMDM Disease mutations120224
Blocks (Seattle)TMEM45B
SuperfamilyQ96B21
Human Protein Atlas [tissue]ENSG00000151715-TMEM45B [tissue]
Peptide AtlasQ96B21
IPIIPI00059683   
Protein Interaction databases
DIP (DOE-UCLA)Q96B21
IntAct (EBI)Q96B21
FunCoupENSG00000151715
BioGRIDTMEM45B
STRING (EMBL)TMEM45B
ZODIACTMEM45B
Ontologies - Pathways
QuickGOQ96B21
Ontology : AmiGOintegral component of membrane  
Ontology : EGO-EBIintegral component of membrane  
NDEx NetworkTMEM45B
Atlas of Cancer Signalling NetworkTMEM45B
Wikipedia pathwaysTMEM45B
Orthology - Evolution
OrthoDB120224
GeneTree (enSembl)ENSG00000151715
Phylogenetic Trees/Animal Genes : TreeFamTMEM45B
HOGENOMQ96B21
Homologs : HomoloGeneTMEM45B
Homology/Alignments : Family Browser (UCSC)TMEM45B
Gene fusions - Rearrangements
Fusion : QuiverTMEM45B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTMEM45B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TMEM45B
dbVarTMEM45B
ClinVarTMEM45B
1000_GenomesTMEM45B 
Exome Variant ServerTMEM45B
GNOMAD BrowserENSG00000151715
Varsome BrowserTMEM45B
Genetic variants : HAPMAP120224
Genomic Variants (DGV)TMEM45B [DGVbeta]
DECIPHERTMEM45B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTMEM45B 
Mutations
ICGC Data PortalTMEM45B 
TCGA Data PortalTMEM45B 
Broad Tumor PortalTMEM45B
OASIS PortalTMEM45B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTMEM45B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTMEM45B
Mutations and Diseases : HGMDTMEM45B
BioMutasearch TMEM45B
DgiDB (Drug Gene Interaction Database)TMEM45B
DoCM (Curated mutations)TMEM45B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TMEM45B (select a term)
intoGenTMEM45B
Cancer3DTMEM45B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTMEM45B
MedgenTMEM45B
Genetic Testing Registry TMEM45B
NextProtQ96B21 [Medical]
TSGene120224
GENETestsTMEM45B
Target ValidationTMEM45B
Huge Navigator TMEM45B [HugePedia]
snp3D : Map Gene to Disease120224
BioCentury BCIQTMEM45B
ClinGenTMEM45B
Clinical trials, drugs, therapy
Protein Interactions : CTD120224
Pharm GKB GenePA134909603
Clinical trialTMEM45B
Miscellaneous
canSAR (ICR)TMEM45B (select the gene name)
HarmonizomeTMEM45B
DataMed IndexTMEM45B
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTMEM45B
EVEXTMEM45B
GoPubMedTMEM45B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jul 16 15:39:51 CEST 2020
Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.