TMEM74 (transmembrane protein 74)

2007-04-01  

Identity

HGNC
LOCATION
8q23.1
LOCUSID
ALIAS
NET36
FUSION GENES

Other Information

Locus ID:

NCBI: 157753
MIM: 613935
HGNC: 26409
Ensembl: ENSG00000164841

Variants:

dbSNP: 157753
ClinVar: 157753
TCGA: ENSG00000164841
COSMIC: TMEM74

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164841ENST00000297459Q96NL1
ENSG00000164841ENST00000297459A0A024R9D4

Expression (GTEx)

0
1
2
3
4

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
182949592008TMEM74, a lysosome and autophagosome protein, regulates autophagy.19
290484332017TMEM74 promotes tumor cell survival by inducing autophagy via interactions with ATG16L1 and ATG9A.3
284124122017Autophagy regulatory molecule, TMEM74, interacts with BIK and inhibits BIK-induced apoptosis.2

Citation

Dessen P

TMEM74 (transmembrane protein 74)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47255/tmem74