TMEM74 (transmembrane protein 74)

2007-04-01  

Identity

HGNC
LOCATION
8q23.1
LOCUSID
ALIAS
NET36
FUSION GENES

Other Information

Locus ID:

NCBI: 157753
MIM: 613935
HGNC: 26409
Ensembl: ENSG00000164841

Variants:

dbSNP: 157753
ClinVar: 157753
TCGA: ENSG00000164841
COSMIC: TMEM74

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164841ENST00000297459Q96NL1
ENSG00000164841ENST00000297459A0A024R9D4

Expression (GTEx)

0
1
2
3
4

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
341321742022Genome-wide association study detected novel susceptibility genes for social cognition impairment in people with schizophrenia.3
341321742022Genome-wide association study detected novel susceptibility genes for social cognition impairment in people with schizophrenia.3
296299522019The Expression of TMEM74 in Liver Cancer and Lung Cancer Correlating With Survival Outcomes.6
296299522019The Expression of TMEM74 in Liver Cancer and Lung Cancer Correlating With Survival Outcomes.6
284124122017Autophagy regulatory molecule, TMEM74, interacts with BIK and inhibits BIK-induced apoptosis.8
290484332017TMEM74 promotes tumor cell survival by inducing autophagy via interactions with ATG16L1 and ATG9A.11
284124122017Autophagy regulatory molecule, TMEM74, interacts with BIK and inhibits BIK-induced apoptosis.8
290484332017TMEM74 promotes tumor cell survival by inducing autophagy via interactions with ATG16L1 and ATG9A.11
182949592008TMEM74, a lysosome and autophagosome protein, regulates autophagy.25
182949592008TMEM74, a lysosome and autophagosome protein, regulates autophagy.25

Citation

Dessen P

TMEM74 (transmembrane protein 74)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47255/tmem74