TMEM98 (transmembrane protein 98)

2003-05-01  

Identity

HGNC
LOCATION
17q11.2
LOCUSID
ALIAS
TADA1
FUSION GENES

Other Information

Locus ID:

NCBI: 26022
MIM: 615949
HGNC: 24529
Ensembl: ENSG00000006042

Variants:

dbSNP: 26022
ClinVar: 26022
TCGA: ENSG00000006042
COSMIC: TMEM98

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000006042ENST00000261713J9JIC8
ENSG00000006042ENST00000394642Q9Y2Y6
ENSG00000006042ENST00000395149C9J3Y0
ENSG00000006042ENST00000439138C9J6Q8
ENSG00000006042ENST00000578289J3QS57
ENSG00000006042ENST00000579849Q9Y2Y6
ENSG00000006042ENST00000583437J3QLG7

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
374199422023Phenotypic consequences of a nanophthalmos-associated TMEM98 variant in human and mouse.0
374199422023Phenotypic consequences of a nanophthalmos-associated TMEM98 variant in human and mouse.0
358663952022Tumor-Suppressor Gene Transmembrane Protein 98 Promotes Proliferation and Inhibits Apoptosis in Ovarian Cancer.1
358663952022Tumor-Suppressor Gene Transmembrane Protein 98 Promotes Proliferation and Inhibits Apoptosis in Ovarian Cancer.1
335964432021A novel proline substitution (Arg201Pro) in alpha helix 8 of TMEM98 causes autosomal dominant nanophthalmos-4, closed angle glaucoma and attenuated visual acuity.1
335964432021A novel proline substitution (Arg201Pro) in alpha helix 8 of TMEM98 causes autosomal dominant nanophthalmos-4, closed angle glaucoma and attenuated visual acuity.1
323793722020TMEM98 mRNA promotes proliferation and invasion of gastric cells by directly interacting with NF90 protein.2
332039482020Novel TMEM98, MFRP, PRSS56 variants in a large United States high hyperopia and nanophthalmos cohort.8
323793722020TMEM98 mRNA promotes proliferation and invasion of gastric cells by directly interacting with NF90 protein.2
332039482020Novel TMEM98, MFRP, PRSS56 variants in a large United States high hyperopia and nanophthalmos cohort.8
312660592019Missense Mutations in the Human Nanophthalmos Gene TMEM98 Cause Retinal Defects in the Mouse.9
312660592019Missense Mutations in the Human Nanophthalmos Gene TMEM98 Cause Retinal Defects in the Mouse.9
303387882018MicroRNA-219-5p inhibits wound healing by targeting TMEM98 in keratinocytes under normoxia and hypoxia condition.4
303387882018MicroRNA-219-5p inhibits wound healing by targeting TMEM98 in keratinocytes under normoxia and hypoxia condition.4
263927402015Novel TMEM98 mutations in pedigrees with autosomal dominant nanophthalmos.19

Citation

Dessen P

TMEM98 (transmembrane protein 98)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/40319/tmem98