Identity
HGNC
LOCATION
9q22.33
LOCUSID
ALIAS
D9S57E,ETMOD,TMOD
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7111
MIM: 190930
HGNC: 11871
Ensembl: ENSG00000136842
Variants:
dbSNP: 7111
ClinVar: 7111
TCGA: ENSG00000136842
COSMIC: TMOD1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000136842 | ENST00000259365 | P28289 |
| ENSG00000136842 | ENST00000375175 | P28289 |
| ENSG00000136842 | ENST00000395211 | P28289 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Muscle contraction | REACTOME | R-HSA-397014 |
| Striated Muscle Contraction | REACTOME | R-HSA-390522 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38168645 | 2024 | Recessive TMOD1 mutation causes childhood cardiomyopathy. | 0 |
| 38168645 | 2024 | Recessive TMOD1 mutation causes childhood cardiomyopathy. | 0 |
| 36316666 | 2022 | Suggestive evidence of the genetic association of TMOD1 and PTCSC2 polymorphisms with thyroid carcinoma in the Chinese Han population. | 0 |
| 36316666 | 2022 | Suggestive evidence of the genetic association of TMOD1 and PTCSC2 polymorphisms with thyroid carcinoma in the Chinese Han population. | 0 |
| 32037094 | 2020 | Tropomodulins Control the Balance between Protrusive and Contractile Structures by Stabilizing Actin-Tropomyosin Filaments. | 14 |
| 32937160 | 2020 | MicroRNA-885 regulates the growth and epithelial mesenchymal transition of human liver cancer cells by suppressing tropomodulin 1 expression. | 3 |
| 32037094 | 2020 | Tropomodulins Control the Balance between Protrusive and Contractile Structures by Stabilizing Actin-Tropomyosin Filaments. | 14 |
| 32937160 | 2020 | MicroRNA-885 regulates the growth and epithelial mesenchymal transition of human liver cancer cells by suppressing tropomodulin 1 expression. | 3 |
| 31364131 | 2019 | Targeted regulation of miR-17-5p on TMOD1 promotes the development of cardia cancer. | 2 |
| 31364131 | 2019 | Targeted regulation of miR-17-5p on TMOD1 promotes the development of cardia cancer. | 2 |
| 28729432 | 2017 | Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome. | 17 |
| 28729432 | 2017 | Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome. | 17 |
| 26873245 | 2016 | Localization of the binding interface between leiomodin-2 and α-tropomyosin. | 16 |
| 26873245 | 2016 | Localization of the binding interface between leiomodin-2 and α-tropomyosin. | 16 |
| 25398440 | 2015 | Tropomodulin 1 expression driven by NF-κB enhances breast cancer growth. | 16 |
Citation
Dessen P
TMOD1 (tropomodulin 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43775/tmod1
