TMPRSS11B (transmembrane serine protease 11B)

2021-06-01  

Identity

HGNC
TMPRSS11B
LOCATION
4q13.2
LOCUSID
132724
ALIAS
HATL5

Other Information

Locus ID:

NCBI: 132724
HGNC: 25398
Ensembl: ENSG00000185873

Variants:

dbSNP: 132724
ClinVar: 132724
TCGA: ENSG00000185873
COSMIC: TMPRSS11B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185873ENST00000332644Q86T26

Expression (GTEx)

0
100
200
300
400
500
600
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
179751192008Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study.65
190230992009Gene variants associated with ischemic stroke: the cardiovascular health study.16
244983512014HATL5: a cell surface serine protease differentially expressed in epithelial cancers.13
304630172018Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism.7

Citation

Dessen P

TMPRSS11B (transmembrane serine protease 11B)

Atlas Genet Cytogenet Oncol Haematol. 2021-06-01

Online version: http://atlasgeneticsoncology.org/gene/58249/tmprss11b