TMPRSS11E (transmembrane serine protease 11E)

2016-08-01  

Identity

HGNC
LOCATION
4q13.2
LOCUSID
ALIAS
DESC1,TMPRSS11E2
FUSION GENES

Other Information

Locus ID:

NCBI: 28983
MIM: 610399
HGNC: 24465
Ensembl: ENSG00000087128

Variants:

dbSNP: 28983
ClinVar: 28983
TCGA: ENSG00000087128
COSMIC: TMPRSS11E

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000087128ENST00000305363Q9UL52
ENSG00000087128ENST00000510647H0Y9G7

Expression (GTEx)

0
50
100
150
200
250
300

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
251228022014DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.29
173888112007Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family.14
268563902016DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by downregulating the EGFR/AKT pathway in esophageal squamous cell carcinoma.11

Citation

Dessen P

TMPRSS11E (transmembrane serine protease 11E)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55905/tmprss11e