TMPRSS13 (transmembrane serine protease 13)

2014-11-01  

Identity

HGNC
TMPRSS13
LOCATION
11q23.3
LOCUSID
84000
ALIAS
MSP,MSPL,MSPS,TMPRSS11

Other Information

Locus ID:

NCBI: 84000
MIM: 610050
HGNC: 29808
Ensembl: ENSG00000137747

Variants:

dbSNP: 84000
ClinVar: 84000
TCGA: ENSG00000137747
COSMIC: TMPRSS13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137747ENST00000430170Q9BYE2
ENSG00000137747ENST00000445164Q9BYE2
ENSG00000137747ENST00000524993Q9BYE2
ENSG00000137747ENST00000526090Q9BYE2
ENSG00000137747ENST00000528135E9PR79
ENSG00000137747ENST00000528626Q9BYE2

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Influenza AKEGGko05164
Influenza AKEGGhsa05164

References

Pubmed IDYearTitleCitations
202199062010Novel type II transmembrane serine proteases, MSPL and TMPRSS13, Proteolytically activate membrane fusion activity of the hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication.35
251228022014DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.29
209776752010TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor.18
179815852008MSPL/TMPRSS13.7
287102772017Phosphorylation of the type II transmembrane serine protease, TMPRSS13, in hepatocyte growth factor activator inhibitor-1 and -2-mediated cell-surface localization.2

Citation

Dessen P

TMPRSS13 (transmembrane serine protease 13)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75014/tmprss13