Identity
HGNC
LOCATION
8p21.3
LOCUSID
ALIAS
CD262,DR5,KILLER,KILLER/DR5,TRAIL-R2,TRAILR2,TRICK2,TRICK2A,TRICK2B,TRICKB,ZTNFR9
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8795
MIM: 603612
HGNC: 11905
Ensembl: ENSG00000120889
Variants:
dbSNP: 8795
ClinVar: 8795
TCGA: ENSG00000120889
COSMIC: TNFRSF10B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000120889 | ENST00000276431 | O14763 |
| ENSG00000120889 | ENST00000347739 | O14763 |
| ENSG00000120889 | ENST00000523504 | E9PBT3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36791922 | 2023 | TNFRSF10B is involved in motor dysfunction in Parkinson's disease by regulating exosomal α-synuclein secretion from microglia. | 0 |
| 36888983 | 2023 | TRAIL or TRAIL-R2 as a Predictive Biomarker for Mortality or Cardiovascular Events: A Systematic Review and Meta-analysis. | 2 |
| 37879960 | 2023 | Death receptor 5 promotes tumor progression in gastric cancer. | 1 |
| 36791922 | 2023 | TNFRSF10B is involved in motor dysfunction in Parkinson's disease by regulating exosomal α-synuclein secretion from microglia. | 0 |
| 36888983 | 2023 | TRAIL or TRAIL-R2 as a Predictive Biomarker for Mortality or Cardiovascular Events: A Systematic Review and Meta-analysis. | 2 |
| 37879960 | 2023 | Death receptor 5 promotes tumor progression in gastric cancer. | 1 |
| 34728311 | 2022 | Enhanced extrinsic apoptosis of therapy-induced senescent cancer cells using a death receptor 5 (DR5) selective agonist. | 8 |
| 35744931 | 2022 | Induction of DR5-Dependent Apoptosis by PGA(2) through ATF4-CHOP Pathway. | 3 |
| 35822538 | 2022 | Elevated soluble death receptor 5 can predict poor prognosis in patients with acute respiratory distress syndrome. | 0 |
| 36012252 | 2022 | Restoring TRAILR2/DR5-Mediated Activation of Apoptosis upon Endoplasmic Reticulum Stress as a Therapeutic Strategy in Cancer. | 2 |
| 36153316 | 2022 | Inhibition of USP1 enhances anticancer drugs-induced cancer cell death through downregulation of survivin and miR-216a-5p-mediated upregulation of DR5. | 9 |
| 34728311 | 2022 | Enhanced extrinsic apoptosis of therapy-induced senescent cancer cells using a death receptor 5 (DR5) selective agonist. | 8 |
| 35744931 | 2022 | Induction of DR5-Dependent Apoptosis by PGA(2) through ATF4-CHOP Pathway. | 3 |
| 35822538 | 2022 | Elevated soluble death receptor 5 can predict poor prognosis in patients with acute respiratory distress syndrome. | 0 |
| 36012252 | 2022 | Restoring TRAILR2/DR5-Mediated Activation of Apoptosis upon Endoplasmic Reticulum Stress as a Therapeutic Strategy in Cancer. | 2 |
Citation
Dessen P
TNFRSF10B (TNF receptor superfamily member 10b)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42606/tnfrsf10b
