Identity
HGNC
LOCATION
17p13.1
LOCUSID
ALIAS
APO3L,DR3LG,TNLG4A,TWEAK
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8742
MIM: 602695
HGNC: 11927
Ensembl: ENSG00000239697
Variants:
dbSNP: 8742
ClinVar: 8742
TCGA: ENSG00000239697
COSMIC: TNFSF12
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000239697 | ENST00000293825 | O43508 |
| ENSG00000239697 | ENST00000293825 | Q4ACW9 |
| ENSG00000239697 | ENST00000322272 | C0H5Y4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38437928 | 2024 | Sarcopenia is associated with hypomethylation of TWEAK and increased plasma levels of TWEAK and its downstream inflammatory factor TNF-α in older adults: A case-control study. | 0 |
| 38932454 | 2024 | Genetically predicted TWEAK mediates the association between lipidome and Keratinocyte Carcinomas. | 1 |
| 38437928 | 2024 | Sarcopenia is associated with hypomethylation of TWEAK and increased plasma levels of TWEAK and its downstream inflammatory factor TNF-α in older adults: A case-control study. | 0 |
| 38932454 | 2024 | Genetically predicted TWEAK mediates the association between lipidome and Keratinocyte Carcinomas. | 1 |
| 36418949 | 2023 | Status of TWEAK DNA methylation and mRNA expression in systemic lupus erythematosus. | 0 |
| 36709605 | 2023 | TWEAK/Fn14 signaling may function as a reactive compensatory mechanism against extracellular matrix accumulation in keloid fibroblasts. | 0 |
| 36716919 | 2023 | Relief of Extracellular Matrix Deposition Repression by Downregulation of IRF1-Mediated TWEAK/Fn14 Signaling in Keloids. | 2 |
| 36916753 | 2023 | TWEAK and Fn14 are overexpressed in immune-mediated necrotizing myopathy: implications for muscle damage and repair. | 1 |
| 37466605 | 2023 | Sclerostin and TNF-related weak inducer of apoptosis: can they be important in the patients with glomerulonephritis? | 0 |
| 38995299 | 2023 | The Relationship between Serum TWEAK Levels and Carotid Intima-media Thickness in Patients with Fabry Disease. | 0 |
| 36418949 | 2023 | Status of TWEAK DNA methylation and mRNA expression in systemic lupus erythematosus. | 0 |
| 36709605 | 2023 | TWEAK/Fn14 signaling may function as a reactive compensatory mechanism against extracellular matrix accumulation in keloid fibroblasts. | 0 |
| 36716919 | 2023 | Relief of Extracellular Matrix Deposition Repression by Downregulation of IRF1-Mediated TWEAK/Fn14 Signaling in Keloids. | 2 |
| 36916753 | 2023 | TWEAK and Fn14 are overexpressed in immune-mediated necrotizing myopathy: implications for muscle damage and repair. | 1 |
| 37466605 | 2023 | Sclerostin and TNF-related weak inducer of apoptosis: can they be important in the patients with glomerulonephritis? | 0 |
Citation
Dessen P
TNFSF12 (TNF superfamily member 12)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/42634/tnfsf12
