Identity
HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
CD258,HVEML,LIGHT,LTg
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8740
MIM: 604520
HGNC: 11930
Ensembl: ENSG00000125735
Variants:
dbSNP: 8740
ClinVar: 8740
TCGA: ENSG00000125735
COSMIC: TNFSF14
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000125735 | ENST00000245912 | O43557 |
| ENSG00000125735 | ENST00000599359 | O43557 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37722959 | 2024 | Increased expression of TNFRSF14 and LIGHT in biliary epithelial cells of patients with primary sclerosing cholangitis. | 0 |
| 38235898 | 2024 | TNFSF14 mediates the impact of docosahexaenoic acid on atopic dermatitis: a Mendelian randomization study. | 0 |
| 37722959 | 2024 | Increased expression of TNFRSF14 and LIGHT in biliary epithelial cells of patients with primary sclerosing cholangitis. | 0 |
| 38235898 | 2024 | TNFSF14 mediates the impact of docosahexaenoic acid on atopic dermatitis: a Mendelian randomization study. | 0 |
| 36917420 | 2023 | High levels of LIGHT/TNFSF14 in patients with Prader-Willi syndrome. | 2 |
| 37408308 | 2023 | LIGHT/TNFSF14 promotes CAR-T cell trafficking and cytotoxicity through reversing immunosuppressive tumor microenvironment. | 5 |
| 37552689 | 2023 | LIGHT (TNFSF14) promotes the differentiation of human bone marrow-derived mesenchymal stem cells into functional hepatocyte-like cells. | 0 |
| 36917420 | 2023 | High levels of LIGHT/TNFSF14 in patients with Prader-Willi syndrome. | 2 |
| 37408308 | 2023 | LIGHT/TNFSF14 promotes CAR-T cell trafficking and cytotoxicity through reversing immunosuppressive tumor microenvironment. | 5 |
| 37552689 | 2023 | LIGHT (TNFSF14) promotes the differentiation of human bone marrow-derived mesenchymal stem cells into functional hepatocyte-like cells. | 0 |
| 34838790 | 2022 | The Contribution of LIGHT (TNFSF14) to the Development of Systemic Sclerosis by Modulating IL-6 and T Helper Type 1 Chemokine Expression in Dermal Fibroblasts. | 1 |
| 34903876 | 2022 | LIGHT controls distinct homeostatic and inflammatory gene expression profiles in esophageal fibroblasts via differential HVEM and LTβR-mediated mechanisms. | 7 |
| 35987137 | 2022 | A LIGHT-HVEM/LTβR axis contributes to the fibrosis of intrauterine adhesion. | 1 |
| 34838790 | 2022 | The Contribution of LIGHT (TNFSF14) to the Development of Systemic Sclerosis by Modulating IL-6 and T Helper Type 1 Chemokine Expression in Dermal Fibroblasts. | 1 |
| 34903876 | 2022 | LIGHT controls distinct homeostatic and inflammatory gene expression profiles in esophageal fibroblasts via differential HVEM and LTβR-mediated mechanisms. | 7 |
Citation
Dessen P
TNFSF14 (TNF superfamily member 14)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/42637/tnfsf14
