Identity
HGNC
LOCATION
10q23.32
LOCUSID
ALIAS
ARTD6,PARP-5b,PARP-5c,PARP5B,PARP5C,TANK2,TNKL,pART6
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80351
MIM: 607128
HGNC: 15677
Ensembl: ENSG00000107854
Variants:
dbSNP: 80351
ClinVar: 80351
TCGA: ENSG00000107854
COSMIC: TNKS2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000107854 | ENST00000371627 | Q9H2K2 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34357507 | 2022 | miR-582-5p inhibits migration and chemo-resistant capabilities of colorectal cancer cells by targeting TNKS2. | 1 |
| 34710250 | 2022 | PARP5B is required for nonhomologous end joining during tumorigenesis in vivo. | 2 |
| 34861798 | 2022 | Down-regulation of hsa_circ_0045474 induces macrophage autophagy in tuberculosis via miR-582-5p/TNKS2 axis. | 7 |
| 35733260 | 2022 | Tankyrases inhibit innate antiviral response by PARylating VISA/MAVS and priming it for RNF146-mediated ubiquitination and degradation. | 12 |
| 34357507 | 2022 | miR-582-5p inhibits migration and chemo-resistant capabilities of colorectal cancer cells by targeting TNKS2. | 1 |
| 34710250 | 2022 | PARP5B is required for nonhomologous end joining during tumorigenesis in vivo. | 2 |
| 34861798 | 2022 | Down-regulation of hsa_circ_0045474 induces macrophage autophagy in tuberculosis via miR-582-5p/TNKS2 axis. | 7 |
| 35733260 | 2022 | Tankyrases inhibit innate antiviral response by PARylating VISA/MAVS and priming it for RNF146-mediated ubiquitination and degradation. | 12 |
| 33099847 | 2021 | MicroRNA-206 inhibits influenza A virus replication by targeting tankyrase 2. | 10 |
| 33361107 | 2021 | Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1. | 18 |
| 33849554 | 2021 | MicroRNA-490-3p inhibits migration and chemoresistance of colorectal cancer cells via targeting TNKS2. | 6 |
| 33923443 | 2021 | Arpin Regulates Migration Persistence by Interacting with Both Tankyrases and the Arp2/3 Complex. | 5 |
| 34112112 | 2021 | Mapping methylation quantitative trait loci in cardiac tissues nominates risk loci and biological pathways in congenital heart disease. | 5 |
| 33099847 | 2021 | MicroRNA-206 inhibits influenza A virus replication by targeting tankyrase 2. | 10 |
| 33361107 | 2021 | Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1. | 18 |
Citation
Dessen P
TNKS2 (tankyrase 2)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43535/tnks2
