Identity
HGNC
LOCATION
8q24.3
LOCUSID
ALIAS
IKBR,NFKBIL2,SEMDSP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4796
MIM: 604546
HGNC: 7801
Ensembl: ENSG00000160949
Variants:
dbSNP: 4796
ClinVar: 4796
TCGA: ENSG00000160949
COSMIC: TONSL
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000160949 | ENST00000409379 | Q96HA7 |
| ENSG00000160949 | ENST00000613741 | A0A087X1F6 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36622344 | 2023 | MMS22L-TONSL functions in sister chromatid cohesion in a pathway parallel to DSCC1-RFC. | 4 |
| 37057595 | 2023 | TONSL Is an Immortalizing Oncogene and a Therapeutic Target in Breast Cancer. | 3 |
| 37298484 | 2023 | Oncogenic Impact of TONSL, a Homologous Recombination Repair Protein at the Replication Fork, in Cancer Stem Cells. | 1 |
| 36622344 | 2023 | MMS22L-TONSL functions in sister chromatid cohesion in a pathway parallel to DSCC1-RFC. | 4 |
| 37057595 | 2023 | TONSL Is an Immortalizing Oncogene and a Therapeutic Target in Breast Cancer. | 3 |
| 37298484 | 2023 | Oncogenic Impact of TONSL, a Homologous Recombination Repair Protein at the Replication Fork, in Cancer Stem Cells. | 1 |
| 32959051 | 2020 | Novel TONSL variants cause SPONASTRIME dysplasia and associate with spontaneous chromosome breaks, defective cell proliferation and apoptosis. | 1 |
| 32959051 | 2020 | Novel TONSL variants cause SPONASTRIME dysplasia and associate with spontaneous chromosome breaks, defective cell proliferation and apoptosis. | 1 |
| 30723051 | 2019 | Overexpression of TONSL might be an independent unfavorable prognostic indicator in hepatocellular carcinoma. | 6 |
| 30773277 | 2019 | Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes. | 13 |
| 30773278 | 2019 | Hypomorphic Mutations in TONSL Cause SPONASTRIME Dysplasia. | 7 |
| 31158361 | 2019 | A novel long non-coding RNA TONSL-AS1 regulates progression of gastric cancer via activating TONSL. | 4 |
| 30723051 | 2019 | Overexpression of TONSL might be an independent unfavorable prognostic indicator in hepatocellular carcinoma. | 6 |
| 30773277 | 2019 | Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes. | 13 |
| 30773278 | 2019 | Hypomorphic Mutations in TONSL Cause SPONASTRIME Dysplasia. | 7 |
Citation
Dessen P
TONSL (tonsoku like, DNA repair protein)
Atlas Genet Cytogenet Oncol Haematol. 2010-12-01
Online version: http://atlasgeneticsoncology.org/gene/51776/tonsl
