Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 63970
MIM: 605426
HGNC: 29984
Ensembl: ENSG00000120471
Variants:
dbSNP: 63970
ClinVar: 63970
TCGA: ENSG00000120471
COSMIC: TP53AIP1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA128406956 | fluorouracil | Chemical | ClinicalAnnotation | associated | PD | ||
| PA443560 | Breast Neoplasms | Disease | ClinicalAnnotation | associated | PD | ||
| PA445113 | Neutropenia | Disease | ClinicalAnnotation | associated | PD | ||
| PA449165 | cyclophosphamide | Chemical | ClinicalAnnotation | associated | PD | ||
| PA449476 | epirubicin | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30864684 | 2019 | Extracellular vesicle‑delivered miR‑505‑5p, as a diagnostic biomarker of early lung adenocarcinoma, inhibits cell apoptosis by targeting TP53AIP1. | 17 |
| 30864684 | 2019 | Extracellular vesicle‑delivered miR‑505‑5p, as a diagnostic biomarker of early lung adenocarcinoma, inhibits cell apoptosis by targeting TP53AIP1. | 17 |
| 29359367 | 2018 | Truncating mutations of TP53AIP1 gene predispose to cutaneous melanoma. | 6 |
| 29359367 | 2018 | Truncating mutations of TP53AIP1 gene predispose to cutaneous melanoma. | 6 |
| 24316591 | 2014 | Anti-apoptotic roles for the mutant p53R248Q through suppression of p53-regulated apoptosis-inducing protein 1 in the RA-derived fibroblast-like synoviocyte cell line MH7A. | 4 |
| 25108434 | 2014 | [Effect of p53-regulated apoptosis-inducing protein 1 transfection on the biological characteristics of PC-3M human prostate cancer cells]. | 0 |
| 24316591 | 2014 | Anti-apoptotic roles for the mutant p53R248Q through suppression of p53-regulated apoptosis-inducing protein 1 in the RA-derived fibroblast-like synoviocyte cell line MH7A. | 4 |
| 25108434 | 2014 | [Effect of p53-regulated apoptosis-inducing protein 1 transfection on the biological characteristics of PC-3M human prostate cancer cells]. | 0 |
| 22334068 | 2012 | Apak competes with p53 for direct binding to intron 1 of p53AIP1 to regulate apoptosis. | 9 |
| 22457820 | 2012 | Prostate cancer risk is not altered by TP53AIP1 germline mutations in a German case-control series. | 4 |
| 22334068 | 2012 | Apak competes with p53 for direct binding to intron 1 of p53AIP1 to regulate apoptosis. | 9 |
| 22457820 | 2012 | Prostate cancer risk is not altered by TP53AIP1 germline mutations in a German case-control series. | 4 |
| 20800603 | 2010 | Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study. | 14 |
| 20800603 | 2010 | Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study. | 14 |
| 19228369 | 2009 | Combination of p53AIP1 and survivin expression is a powerful prognostic marker in non-small cell lung cancer. | 10 |
Citation
Dessen P
TP53AIP1 (tumor protein p53 regulated apoptosis inducing protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2009-03-01
Online version: http://atlasgeneticsoncology.org/gene/50785/tp53aip1
