Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9540
MIM: 605171
HGNC: 19373
Ensembl: ENSG00000115129
Variants:
dbSNP: 9540
ClinVar: 9540
TCGA: ENSG00000115129
COSMIC: TP53I3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000115129 | ENST00000238721 | Q53FA7 |
| ENSG00000115129 | ENST00000335934 | Q53FA7 |
| ENSG00000115129 | ENST00000407482 | Q53FA7 |
| ENSG00000115129 | ENST00000413037 | H7BZH6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30281878 | 2018 | p53-inducible gene 3 promotes cell migration and invasion by activating the FAK/Src pathway in lung adenocarcinoma. | 12 |
| 30334411 | 2018 | PIG3 suppresses gastric cancer proliferation by regulating p53- mediated apoptosis. | 5 |
| 30281878 | 2018 | p53-inducible gene 3 promotes cell migration and invasion by activating the FAK/Src pathway in lung adenocarcinoma. | 12 |
| 30334411 | 2018 | PIG3 suppresses gastric cancer proliferation by regulating p53- mediated apoptosis. | 5 |
| 28259183 | 2017 | PIG3 promotes NSCLC cell mitotic progression and is associated with poor prognosis of NSCLC patients. | 11 |
| 28351326 | 2017 | Suppression of p53-inducible gene 3 is significant for glioblastoma progression and predicts poor patient prognosis. | 6 |
| 28259183 | 2017 | PIG3 promotes NSCLC cell mitotic progression and is associated with poor prognosis of NSCLC patients. | 11 |
| 28351326 | 2017 | Suppression of p53-inducible gene 3 is significant for glioblastoma progression and predicts poor patient prognosis. | 6 |
| 26464464 | 2016 | Reactivation of p53 by a Cytoskeletal Sensor to Control the Balance Between DNA Damage and Tumor Dissemination. | 35 |
| 26472723 | 2016 | Methyl methanesulfonate induces necroptosis in human lung adenoma A549 cells through the PIG-3-reactive oxygen species pathway. | 10 |
| 27029070 | 2016 | Loss of PIG3 increases HIF-1α level by promoting protein synthesis via mTOR pathway in renal cell carcinoma cells. | 3 |
| 26464464 | 2016 | Reactivation of p53 by a Cytoskeletal Sensor to Control the Balance Between DNA Damage and Tumor Dissemination. | 35 |
| 26472723 | 2016 | Methyl methanesulfonate induces necroptosis in human lung adenoma A549 cells through the PIG-3-reactive oxygen species pathway. | 10 |
| 27029070 | 2016 | Loss of PIG3 increases HIF-1α level by promoting protein synthesis via mTOR pathway in renal cell carcinoma cells. | 3 |
| 26133772 | 2015 | PIG3 plays an oncogenic role in papillary thyroid cancer by activating the PI3K/AKT/PTEN pathway. | 19 |
Citation
Dessen P
TP53I3 (tumor protein p53 inducible protein 3)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/42670/tp53i3
