Identity
HGNC
LOCATION
20q11.22
LOCUSID
ALIAS
C20orf110,DOR,PIG-U,PIGU,PINH,dJ1181N3.1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 58476
MIM: 617549
HGNC: 16104
Ensembl: ENSG00000078804
Variants:
dbSNP: 58476
ClinVar: 58476
TCGA: ENSG00000078804
COSMIC: TP53INP2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000078804 | ENST00000374809 | Q8IXH6 |
| ENSG00000078804 | ENST00000374810 | Q8IXH6 |
| ENSG00000078804 | ENST00000414082 | Q5JX66 |
| ENSG00000078804 | ENST00000451665 | Q5JX65 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Autophagy - animal | KEGG | ko04140 |
| Autophagy - animal | KEGG | hsa04140 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37995453 | 2024 | TP53INP2 modulates the malignant progression of colorectal cancer by reducing the inactive form of β-catenin. | 0 |
| 37995453 | 2024 | TP53INP2 modulates the malignant progression of colorectal cancer by reducing the inactive form of β-catenin. | 0 |
| 36650573 | 2023 | Inactivation of ZSCAN18 by promoter hypermethylation drives the proliferation via attenuating TP53INP2-mediated autophagy in gastric cancer cells. | 5 |
| 36675134 | 2023 | Cytoplasmic Expression of TP53INP2 Modulated by Demethylase FTO and Mutant NPM1 Promotes Autophagy in Leukemia Cells. | 8 |
| 36650573 | 2023 | Inactivation of ZSCAN18 by promoter hypermethylation drives the proliferation via attenuating TP53INP2-mediated autophagy in gastric cancer cells. | 5 |
| 36675134 | 2023 | Cytoplasmic Expression of TP53INP2 Modulated by Demethylase FTO and Mutant NPM1 Promotes Autophagy in Leukemia Cells. | 8 |
| 35615533 | 2022 | Overexpression of TP53INP2 Promotes Apoptosis in Clear Cell Renal Cell Cancer via Caspase-8/TRAF6 Signaling Pathway. | 4 |
| 35954230 | 2022 | TP53INP2 Contributes to TGF-β2-Induced Autophagy during the Epithelial-Mesenchymal Transition in Posterior Capsular Opacification Development. | 4 |
| 35615533 | 2022 | Overexpression of TP53INP2 Promotes Apoptosis in Clear Cell Renal Cell Cancer via Caspase-8/TRAF6 Signaling Pathway. | 4 |
| 35954230 | 2022 | TP53INP2 Contributes to TGF-β2-Induced Autophagy during the Epithelial-Mesenchymal Transition in Posterior Capsular Opacification Development. | 4 |
| 31931658 | 2020 | The bifunctional role of TP53INP2 in transcription and autophagy. | 10 |
| 32535070 | 2020 | Dysregulation in the expression of (lncRNA-TSIX, TP53INP2 mRNA, miRNA-1283) in spinal cord injury. | 5 |
| 31931658 | 2020 | The bifunctional role of TP53INP2 in transcription and autophagy. | 10 |
| 32535070 | 2020 | Dysregulation in the expression of (lncRNA-TSIX, TP53INP2 mRNA, miRNA-1283) in spinal cord injury. | 5 |
| 30767704 | 2019 | TP53INP2 contributes to autophagosome formation by promoting LC3-ATG7 interaction. | 39 |
Citation
Dessen P
TP53INP2 (tumor protein p53 inducible nuclear protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2004-08-01
Online version: http://atlasgeneticsoncology.org/gene/42920/tp53inp2
