Identity
HGNC
LOCATION
20q13.12
LOCUSID
ALIAS
BUD32,C20orf64,GAMOS4,Nori-2,Nori-2p,PRPK,TPRKB,dJ101A2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 112858
MIM: 608679
HGNC: 16197
Ensembl: ENSG00000172315
Variants:
dbSNP: 112858
ClinVar: 112858
TCGA: ENSG00000172315
COSMIC: TP53RK
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000172315 | ENST00000372102 | Q5JZ02 |
| ENSG00000172315 | ENST00000372114 | Q96S44 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37382161 | 2023 | TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5. | 0 |
| 37382161 | 2023 | TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5. | 0 |
| 33547416 | 2021 | Crystal structure of the human PRPK-TPRKB complex. | 6 |
| 33547416 | 2021 | Crystal structure of the human PRPK-TPRKB complex. | 6 |
| 29483219 | 2018 | Targeting PRPK Function Blocks Colon Cancer Metastasis. | 13 |
| 30053862 | 2018 | A familial case of Galloway-Mowat syndrome due to a novel TP53RK mutation: a case report. | 8 |
| 29483219 | 2018 | Targeting PRPK Function Blocks Colon Cancer Metastasis. | 13 |
| 30053862 | 2018 | A familial case of Galloway-Mowat syndrome due to a novel TP53RK mutation: a case report. | 8 |
| 28082445 | 2017 | p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma. | 28 |
| 28082445 | 2017 | p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma. | 28 |
| 24351856 | 2014 | An integrative study of the genetic, social and environmental determinants of chronic kidney disease characterized by tubulointerstitial damages in the North Central Region of Sri Lanka. | 38 |
| 24351856 | 2014 | An integrative study of the genetic, social and environmental determinants of chronic kidney disease characterized by tubulointerstitial damages in the North Central Region of Sri Lanka. | 38 |
| 20677014 | 2010 | An approach based on a genome-wide association study reveals candidate loci for narcolepsy. | 19 |
| 20677014 | 2010 | An approach based on a genome-wide association study reveals candidate loci for narcolepsy. | 19 |
| 17712528 | 2007 | Phosphorylation and activation of the atypical kinase p53-related protein kinase (PRPK) by Akt/PKB. | 16 |
Citation
Dessen P
TP53RK (TP53 regulating kinase)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43537/tp53rk
