Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TPRA1 (transmembrane protein adipocyte associated 1)

Identity

Alias_namesGPR175
G protein-coupled receptor 175
transmembrane protein, adipocyte asscociated 1
Alias_symbol (synonym)TPRA40
FLJ32197
TMEM227
Other alias
HGNC (Hugo) TPRA1
LocusID (NCBI) 131601
Atlas_Id 75079
Location 3q21.3  [Link to chromosome band 3q21]
Location_base_pair Starts at 127573064 and ends at 127590759 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CCDC90B (11q14.1) / TPRA1 (3q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TPRA1   30413
Cards
Entrez_Gene (NCBI)TPRA1  131601  transmembrane protein adipocyte associated 1
AliasesGPR175; TMEM227; TPRA40
GeneCards (Weizmann)TPRA1
Ensembl hg19 (Hinxton)ENSG00000163870 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163870 [Gene_View]  ENSG00000163870 [Sequence]  chr3:127573064-127590759 [Contig_View]  TPRA1 [Vega]
ICGC DataPortalENSG00000163870
TCGA cBioPortalTPRA1
AceView (NCBI)TPRA1
Genatlas (Paris)TPRA1
WikiGenes131601
SOURCE (Princeton)TPRA1
Genetics Home Reference (NIH)TPRA1
Genomic and cartography
GoldenPath hg38 (UCSC)TPRA1  -     chr3:127573064-127590759 -  3q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TPRA1  -     3q21.3   [Description]    (hg19-Feb_2009)
GoldenPathTPRA1 - 3q21.3 [CytoView hg19]  TPRA1 - 3q21.3 [CytoView hg38]
ImmunoBaseENSG00000163870
Mapping of homologs : NCBITPRA1 [Mapview hg19]  TPRA1 [Mapview hg38]
OMIM608336   
Gene and transcription
Genbank (Entrez)AB037108 AF289568 AI248453 AK056759 BC017058
RefSeq transcript (Entrez)NM_001136053 NM_001142646 NM_001353001 NM_001353002 NM_001353003 NM_001353004 NM_001353005 NM_001353006 NM_001353007 NM_016372
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TPRA1
Cluster EST : UnigeneHs.617549 [ NCBI ]
CGAP (NCI)Hs.617549
Alternative Splicing GalleryENSG00000163870
Gene ExpressionTPRA1 [ NCBI-GEO ]   TPRA1 [ EBI - ARRAY_EXPRESS ]   TPRA1 [ SEEK ]   TPRA1 [ MEM ]
Gene Expression Viewer (FireBrowse)TPRA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)131601
GTEX Portal (Tissue expression)TPRA1
Human Protein AtlasENSG00000163870-TPRA1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86W33   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86W33  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86W33
Splice isoforms : SwissVarQ86W33
PhosPhoSitePlusQ86W33
Domains : Interpro (EBI)TPRA40   
Domain families : Pfam (Sanger)Tmemb_40 (PF10160)   
Domain families : Pfam (NCBI)pfam10160   
Conserved Domain (NCBI)TPRA1
DMDM Disease mutations131601
Blocks (Seattle)TPRA1
SuperfamilyQ86W33
Human Protein Atlas [tissue]ENSG00000163870-TPRA1 [tissue]
Peptide AtlasQ86W33
HPRD16318
IPIIPI00293000   IPI00103792   IPI00658198   IPI00946169   IPI00797613   IPI00793970   IPI00946669   IPI00945865   
Protein Interaction databases
DIP (DOE-UCLA)Q86W33
IntAct (EBI)Q86W33
FunCoupENSG00000163870
BioGRIDTPRA1
STRING (EMBL)TPRA1
ZODIACTPRA1
Ontologies - Pathways
QuickGOQ86W33
Ontology : AmiGOG protein-coupled receptor activity  protein binding  lipid metabolic process  G protein-coupled receptor signaling pathway  aging  integral component of membrane  embryonic cleavage  negative regulation of mitotic cell cycle phase transition  
Ontology : EGO-EBIG protein-coupled receptor activity  protein binding  lipid metabolic process  G protein-coupled receptor signaling pathway  aging  integral component of membrane  embryonic cleavage  negative regulation of mitotic cell cycle phase transition  
NDEx NetworkTPRA1
Atlas of Cancer Signalling NetworkTPRA1
Wikipedia pathwaysTPRA1
Orthology - Evolution
OrthoDB131601
GeneTree (enSembl)ENSG00000163870
Phylogenetic Trees/Animal Genes : TreeFamTPRA1
HOGENOMQ86W33
Homologs : HomoloGeneTPRA1
Homology/Alignments : Family Browser (UCSC)TPRA1
Gene fusions - Rearrangements
Fusion : QuiverTPRA1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTPRA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TPRA1
dbVarTPRA1
ClinVarTPRA1
1000_GenomesTPRA1 
Exome Variant ServerTPRA1
ExAC (Exome Aggregation Consortium)ENSG00000163870
GNOMAD BrowserENSG00000163870
Varsome BrowserTPRA1
Genetic variants : HAPMAP131601
Genomic Variants (DGV)TPRA1 [DGVbeta]
DECIPHERTPRA1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTPRA1 
Mutations
ICGC Data PortalTPRA1 
TCGA Data PortalTPRA1 
Broad Tumor PortalTPRA1
OASIS PortalTPRA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTPRA1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTPRA1
Mutations and Diseases : HGMDTPRA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TPRA1
DgiDB (Drug Gene Interaction Database)TPRA1
DoCM (Curated mutations)TPRA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TPRA1 (select a term)
intoGenTPRA1
Cancer3DTPRA1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608336   
Orphanet
DisGeNETTPRA1
MedgenTPRA1
Genetic Testing Registry TPRA1
NextProtQ86W33 [Medical]
TSGene131601
GENETestsTPRA1
Target ValidationTPRA1
Huge Navigator TPRA1 [HugePedia]
snp3D : Map Gene to Disease131601
BioCentury BCIQTPRA1
ClinGenTPRA1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD131601
Chemical/Pharm GKB GenePA165698543
Clinical trialTPRA1
Miscellaneous
canSAR (ICR)TPRA1 (select the gene name)
DataMed IndexTPRA1
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTPRA1
EVEXTPRA1
GoPubMedTPRA1
iHOPTPRA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 16:11:06 CEST 2019
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