TRAF3IP3 (TRAF3 interacting protein 3)

2019-04-01  

Identity

HGNC
TRAF3IP3
LOCATION
1q32.2
LOCUSID
80342
ALIAS
T3JAM
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 80342
MIM: 608255
HGNC: 30766
Ensembl: ENSG00000009790

Variants:

dbSNP: 80342
ClinVar: 80342
TCGA: ENSG00000009790
COSMIC: TRAF3IP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000009790ENST00000367023B1AJU2
ENSG00000009790ENST00000367024Q9Y228
ENSG00000009790ENST00000367025Q9Y228
ENSG00000009790ENST00000367026Q9Y228
ENSG00000009790ENST00000400959E2QRE5
ENSG00000009790ENST00000471368H0YF09
ENSG00000009790ENST00000477431C9JBA0
ENSG00000009790ENST00000478359Q9Y228
ENSG00000009790ENST00000479796C9JXB3
ENSG00000009790ENST00000487271C9J0C0

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
145726592003T3JAM, a novel protein that specifically interacts with TRAF3 and promotes the activation of JNK(1).12
178687422007Identification of five human novel genes associated with cell proliferation by cell-based screening from an expressed cDNA ORF library.10
313900912019TRAF3IP3 mediates the recruitment of TRAF3 to MAVS for antiviral innate immunity.4
295539672018TRAF3-interacting protein 3, a new oncotarget, promotes tumor growth in melanoma.2
172778852007TRAF3 interacts with Smac/DIABLO and enhances the proapoptotic effect of Smac/DIABLO in cytoplasm.1

Citation

Dessen P

TRAF3IP3 (TRAF3 interacting protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2019-04-01

Online version: http://atlasgeneticsoncology.org/gene/57909/traf3ip3