Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TRAFD1 (TRAF-type zinc finger domain containing 1)

Identity

Alias (NCBI)FLN29
HGNC (Hugo) TRAFD1
HGNC Alias symbFLN29
LocusID (NCBI) 10906
Atlas_Id 75101
Location 12q24.13  [Link to chromosome band 12q24]
Location_base_pair Starts at 112125545 and ends at 112153604 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MED13L (12q24.21) / TRAFD1 (12q24.13)TRAFD1 (12q24.13) / TRAFD1 (12q24.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  MED13L/TRAFD1 (12q24)

External links

Nomenclature
HGNC (Hugo)TRAFD1   24808
Cards
Entrez_Gene (NCBI)TRAFD1  10906  TRAF-type zinc finger domain containing 1
AliasesFLN29
GeneCards (Weizmann)TRAFD1
Ensembl hg19 (Hinxton)ENSG00000135148 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135148 [Gene_View]  ENSG00000135148 [Sequence]  chr12:112125545-112153604 [Contig_View]  TRAFD1 [Vega]
ICGC DataPortalENSG00000135148
TCGA cBioPortalTRAFD1
AceView (NCBI)TRAFD1
Genatlas (Paris)TRAFD1
WikiGenes10906
SOURCE (Princeton)TRAFD1
Genetics Home Reference (NIH)TRAFD1
Genomic and cartography
GoldenPath hg38 (UCSC)TRAFD1  -     chr12:112125545-112153604 +  12q24.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRAFD1  -     12q24.13   [Description]    (hg19-Feb_2009)
GoldenPathTRAFD1 - 12q24.13 [CytoView hg19]  TRAFD1 - 12q24.13 [CytoView hg38]
ImmunoBaseENSG00000135148
genome Data Viewer NCBITRAFD1 [Mapview hg19]  
OMIM613197   
Gene and transcription
Genbank (Entrez)AB007447 AK122620 AK291331 AK295474 AK309916
RefSeq transcript (Entrez)NM_001143906 NM_006700
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TRAFD1
Alternative Splicing GalleryENSG00000135148
Gene ExpressionTRAFD1 [ NCBI-GEO ]   TRAFD1 [ EBI - ARRAY_EXPRESS ]   TRAFD1 [ SEEK ]   TRAFD1 [ MEM ]
Gene Expression Viewer (FireBrowse)TRAFD1 [ Firebrowse - Broad ]
GenevisibleExpression of TRAFD1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10906
GTEX Portal (Tissue expression)TRAFD1
Human Protein AtlasENSG00000135148-TRAFD1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14545   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14545  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14545
Splice isoforms : SwissVarO14545
PhosPhoSitePlusO14545
Domains : Interpro (EBI)Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TRAFD1
DMDM Disease mutations10906
Blocks (Seattle)TRAFD1
PDB (RSDB)2D9K   
PDB Europe2D9K   
PDB (PDBSum)2D9K   
PDB (IMB)2D9K   
Structural Biology KnowledgeBase2D9K   
SCOP (Structural Classification of Proteins)2D9K   
CATH (Classification of proteins structures)2D9K   
SuperfamilyO14545
Human Protein Atlas [tissue]ENSG00000135148-TRAFD1 [tissue]
Peptide AtlasO14545
HPRD10994
IPIIPI00009146   IPI00908631   IPI01021862   IPI01021369   IPI01021568   IPI01022706   
Protein Interaction databases
DIP (DOE-UCLA)O14545
IntAct (EBI)O14545
FunCoupENSG00000135148
BioGRIDTRAFD1
STRING (EMBL)TRAFD1
ZODIACTRAFD1
Ontologies - Pathways
QuickGOO14545
Ontology : AmiGOprotein binding  negative regulation of innate immune response  metal ion binding  
Ontology : EGO-EBIprotein binding  negative regulation of innate immune response  metal ion binding  
NDEx NetworkTRAFD1
Atlas of Cancer Signalling NetworkTRAFD1
Wikipedia pathwaysTRAFD1
Orthology - Evolution
OrthoDB10906
GeneTree (enSembl)ENSG00000135148
Phylogenetic Trees/Animal Genes : TreeFamTRAFD1
HOGENOMO14545
Homologs : HomoloGeneTRAFD1
Homology/Alignments : Family Browser (UCSC)TRAFD1
Gene fusions - Rearrangements
Fusion : QuiverTRAFD1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRAFD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRAFD1
dbVarTRAFD1
ClinVarTRAFD1
1000_GenomesTRAFD1 
Exome Variant ServerTRAFD1
GNOMAD BrowserENSG00000135148
Varsome BrowserTRAFD1
Genetic variants : HAPMAP10906
Genomic Variants (DGV)TRAFD1 [DGVbeta]
DECIPHERTRAFD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRAFD1 
Mutations
ICGC Data PortalTRAFD1 
TCGA Data PortalTRAFD1 
Broad Tumor PortalTRAFD1
OASIS PortalTRAFD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRAFD1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRAFD1
Mutations and Diseases : HGMDTRAFD1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRAFD1
DgiDB (Drug Gene Interaction Database)TRAFD1
DoCM (Curated mutations)TRAFD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRAFD1 (select a term)
intoGenTRAFD1
Cancer3DTRAFD1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613197   
Orphanet
DisGeNETTRAFD1
MedgenTRAFD1
Genetic Testing Registry TRAFD1
NextProtO14545 [Medical]
TSGene10906
GENETestsTRAFD1
Target ValidationTRAFD1
Huge Navigator TRAFD1 [HugePedia]
snp3D : Map Gene to Disease10906
BioCentury BCIQTRAFD1
ClinGenTRAFD1
Clinical trials, drugs, therapy
Protein Interactions : CTD10906
Pharm GKB GenePA142670704
Clinical trialTRAFD1
Miscellaneous
canSAR (ICR)TRAFD1 (select the gene name)
HarmonizomeTRAFD1
DataMed IndexTRAFD1
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRAFD1
EVEXTRAFD1
GoPubMedTRAFD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 16:33:47 CEST 2020
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