TRERF1 (transcriptional regulating factor 1)

2003-06-01  

Identity

HGNC
LOCATION
6p21.1
LOCUSID
ALIAS
BCAR2,HSA277276,RAPA,TREP132,TReP-132,dJ139D8.5
FUSION GENES

Other Information

Locus ID:

NCBI: 55809
MIM: 610322
HGNC: 18273
Ensembl: ENSG00000124496

Variants:

dbSNP: 55809
ClinVar: 55809
TCGA: ENSG00000124496
COSMIC: TRERF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124496ENST00000340840Q96PN7
ENSG00000124496ENST00000354325Q96PN7
ENSG00000124496ENST00000372917Q96PN7
ENSG00000124496ENST00000372922Q96PN7
ENSG00000124496ENST00000541110Q05GC8

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
170154802006TReP-132 is a novel progesterone receptor coactivator required for the inhibition of breast cancer cell growth and enhancement of differentiation by progesterone.14
121011862002The transcriptional regulating protein of 132 kDa (TReP-132) enhances P450scc gene transcription through interaction with steroidogenic factor-1 in human adrenal cells.13
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
150725592004The transcriptional regulating protein of 132 kDa (TReP-132) differentially influences steroidogenic pathways in human adrenal NCI-H295 cells.7
158998402005TReP-132 controls cell proliferation by regulating the expression of the cyclin-dependent kinase inhibitors p21WAF1/Cip1 and p27Kip1.6
125306632002Function of the transcriptional regulating protein of 132 kDa (TReP-132) on human P450scc gene expression.4
293934342018Novel TRERF1 mutations in Chinese patients with ovarian endometriosis.0

Citation

Dessen P

TRERF1 (transcriptional regulating factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/53315/trerf1