Identity
HGNC
LOCATION
20p13
LOCUSID
ALIAS
C20orf97,NIPK,SINK,SKIP3,TRB3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57761
MIM: 607898
HGNC: 16228
Ensembl: ENSG00000101255
Variants:
dbSNP: 57761
ClinVar: 57761
TCGA: ENSG00000101255
COSMIC: TRIB3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101255 | ENST00000217233 | Q96RU7 |
| ENSG00000101255 | ENST00000422053 | J3KR25 |
| ENSG00000101255 | ENST00000449710 | B0QYQ2 |
| ENSG00000101255 | ENST00000615226 | A0A087WTX3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447197 | Attention Deficit Disorder with Hyperactivity | Disease | ClinicalAnnotation | associated | PD | 29382897 | |
| PA450464 | methylphenidate | Chemical | ClinicalAnnotation | associated | PD | 29382897 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37226405 | 2024 | Integration of dietary nutrition and TRIB3 action into diabetes mellitus. | 1 |
| 38237865 | 2024 | TRIB3-TRIM8 complex drives NAFLD progression by regulating HNF4α stability. | 0 |
| 38372068 | 2024 | m(6)A-induced TRIB3 regulates Hippo pathway through interacting with LATS1 to promote the progression of lung adenocarcinoma. | 0 |
| 38429254 | 2024 | TRIB3 promotes malignancy of head and neck squamous cell carcinoma via inhibiting ferroptosis. | 1 |
| 38561354 | 2024 | TRIB3 promotes the progression of renal cell carcinoma by upregulating the lipid droplet-associated protein PLIN2. | 0 |
| 38696945 | 2024 | TRIB3 promotes the growth of oral squamous cell carcinoma by regulating JNK/JUN-mediated aerobic glycolysis. | 0 |
| 37226405 | 2024 | Integration of dietary nutrition and TRIB3 action into diabetes mellitus. | 1 |
| 38237865 | 2024 | TRIB3-TRIM8 complex drives NAFLD progression by regulating HNF4α stability. | 0 |
| 38372068 | 2024 | m(6)A-induced TRIB3 regulates Hippo pathway through interacting with LATS1 to promote the progression of lung adenocarcinoma. | 0 |
| 38429254 | 2024 | TRIB3 promotes malignancy of head and neck squamous cell carcinoma via inhibiting ferroptosis. | 1 |
| 38561354 | 2024 | TRIB3 promotes the progression of renal cell carcinoma by upregulating the lipid droplet-associated protein PLIN2. | 0 |
| 38696945 | 2024 | TRIB3 promotes the growth of oral squamous cell carcinoma by regulating JNK/JUN-mediated aerobic glycolysis. | 0 |
| 36527874 | 2023 | The functions and molecular mechanisms of Tribbles homolog 3 (TRIB3) implicated in the pathophysiology of cancer. | 4 |
| 37083954 | 2023 | Upregulation of Tribbles decreases body weight and increases sleep duration. | 2 |
| 37717559 | 2023 | Transcription Factor Sox9 Exacerbates Kidney Injury through Inhibition of MicroRNA-96-5p and Activation of the Trib3/IL-6 Axis. | 0 |
Citation
Dessen P
TRIB3 (tribbles pseudokinase 3)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43541/trib3
