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TRIM11 (tripartite motif containing 11)

Identity

Alias (NCBI)BIA1
RNF92
HGNC (Hugo) TRIM11
HGNC Alias symbRNF92
BIA1
HGNC Previous nametripartite motif-containing 11
LocusID (NCBI) 81559
Atlas_Id 53786
Location 1q42.13  [Link to chromosome band 1q42]
Location_base_pair Starts at 228393676 and ends at 228406835 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SIPA1L2 (1q42.2) / TRIM11 (1q42.13)TRIM11 (1q42.13) / SLC2A5 (1p36.23)SIPA1L2 1q42.2 / TRIM11 1q42.13
TRIM11 1q42.13 / SLC2A5 1p36.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(1;1)(p36;q42) TRIM11/SLC2A5
SIPA1L2/TRIM11 (1q42)

External links

Nomenclature
HGNC (Hugo)TRIM11   16281
Cards
Entrez_Gene (NCBI)TRIM11  81559  tripartite motif containing 11
AliasesBIA1; RNF92
GeneCards (Weizmann)TRIM11
Ensembl hg19 (Hinxton)ENSG00000154370 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000154370 [Gene_View]  ENSG00000154370 [Sequence]  chr1:228393676-228406835 [Contig_View]  TRIM11 [Vega]
ICGC DataPortalENSG00000154370
TCGA cBioPortalTRIM11
AceView (NCBI)TRIM11
Genatlas (Paris)TRIM11
WikiGenes81559
SOURCE (Princeton)TRIM11
Genetics Home Reference (NIH)TRIM11
Genomic and cartography
GoldenPath hg38 (UCSC)TRIM11  -     chr1:228393676-228406835 -  1q42.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIM11  -     1q42.13   [Description]    (hg19-Feb_2009)
GoldenPathTRIM11 - 1q42.13 [CytoView hg19]  TRIM11 - 1q42.13 [CytoView hg38]
ImmunoBaseENSG00000154370
genome Data Viewer NCBITRIM11 [Mapview hg19]  
OMIM607868   
Gene and transcription
Genbank (Entrez)AF220125 AF327056 AK074866 AK097825 AK226119
RefSeq transcript (Entrez)NM_145214
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TRIM11
Alternative Splicing GalleryENSG00000154370
Gene ExpressionTRIM11 [ NCBI-GEO ]   TRIM11 [ EBI - ARRAY_EXPRESS ]   TRIM11 [ SEEK ]   TRIM11 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM11 [ Firebrowse - Broad ]
GenevisibleExpression of TRIM11 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81559
GTEX Portal (Tissue expression)TRIM11
Human Protein AtlasENSG00000154370-TRIM11 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96F44   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96F44  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96F44
Splice isoforms : SwissVarQ96F44
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ96F44
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)B30.2/SPRY    Butyrophylin_SPRY    ConA-like_dom_sf    PRY    SPRY_dom    Znf_B-box    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)PRY (PF13765)    SPRY (PF00622)    zf-B_box (PF00643)   
Domain families : Pfam (NCBI)pfam13765    pfam00622    pfam00643   
Domain families : Smart (EMBL)BBOX (SM00336)  PRY (SM00589)  RING (SM00184)  SPRY (SM00449)  
Conserved Domain (NCBI)TRIM11
DMDM Disease mutations81559
Blocks (Seattle)TRIM11
SuperfamilyQ96F44
Human Protein Atlas [tissue]ENSG00000154370-TRIM11 [tissue]
Peptide AtlasQ96F44
HPRD07429
IPIIPI00219527   IPI00385975   IPI00969554   
Protein Interaction databases
DIP (DOE-UCLA)Q96F44
IntAct (EBI)Q96F44
FunCoupENSG00000154370
BioGRIDTRIM11
STRING (EMBL)TRIM11
ZODIACTRIM11
Ontologies - Pathways
QuickGOQ96F44
Ontology : AmiGOprotein binding  nucleoplasm  cytoplasm  cytoplasm  cytosol  transcription factor binding  zinc ion binding  regulation of gene expression  protein ubiquitination  protein ubiquitination  protein domain specific binding  negative regulation of viral transcription  innate immune response  innate immune response  negative regulation of transcription, DNA-templated  negative regulation of viral entry into host cell  positive regulation of viral entry into host cell  negative regulation of neurogenesis  defense response to virus  ubiquitin protein ligase activity  negative regulation of viral release from host cell  negative regulation of viral release from host cell  
Ontology : EGO-EBIprotein binding  nucleoplasm  cytoplasm  cytoplasm  cytosol  transcription factor binding  zinc ion binding  regulation of gene expression  protein ubiquitination  protein ubiquitination  protein domain specific binding  negative regulation of viral transcription  innate immune response  innate immune response  negative regulation of transcription, DNA-templated  negative regulation of viral entry into host cell  positive regulation of viral entry into host cell  negative regulation of neurogenesis  defense response to virus  ubiquitin protein ligase activity  negative regulation of viral release from host cell  negative regulation of viral release from host cell  
NDEx NetworkTRIM11
Atlas of Cancer Signalling NetworkTRIM11
Wikipedia pathwaysTRIM11
Orthology - Evolution
OrthoDB81559
GeneTree (enSembl)ENSG00000154370
Phylogenetic Trees/Animal Genes : TreeFamTRIM11
HOGENOMQ96F44
Homologs : HomoloGeneTRIM11
Homology/Alignments : Family Browser (UCSC)TRIM11
Gene fusions - Rearrangements
Fusion : MitelmanSIPA1L2/TRIM11 [1q42.2/1q42.13]  
Fusion : MitelmanTRIM11/SLC2A5 [1q42.13/1p36.23]  
Fusion PortalSIPA1L2 1q42.2 TRIM11 1q42.13 PRAD
Fusion PortalTRIM11 1q42.13 SLC2A5 1p36.23 BRCA
Fusion : QuiverTRIM11
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM11
dbVarTRIM11
ClinVarTRIM11
1000_GenomesTRIM11 
Exome Variant ServerTRIM11
GNOMAD BrowserENSG00000154370
Varsome BrowserTRIM11
Genetic variants : HAPMAP81559
Genomic Variants (DGV)TRIM11 [DGVbeta]
DECIPHERTRIM11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIM11 
Mutations
ICGC Data PortalTRIM11 
TCGA Data PortalTRIM11 
Broad Tumor PortalTRIM11
OASIS PortalTRIM11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM11  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRIM11
Mutations and Diseases : HGMDTRIM11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRIM11
DgiDB (Drug Gene Interaction Database)TRIM11
DoCM (Curated mutations)TRIM11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRIM11 (select a term)
intoGenTRIM11
Cancer3DTRIM11(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607868   
Orphanet
DisGeNETTRIM11
MedgenTRIM11
Genetic Testing Registry TRIM11
NextProtQ96F44 [Medical]
TSGene81559
GENETestsTRIM11
Target ValidationTRIM11
Huge Navigator TRIM11 [HugePedia]
snp3D : Map Gene to Disease81559
BioCentury BCIQTRIM11
ClinGenTRIM11
Clinical trials, drugs, therapy
Protein Interactions : CTD81559
Pharm GKB GenePA38112
Clinical trialTRIM11
Miscellaneous
canSAR (ICR)TRIM11 (select the gene name)
HarmonizomeTRIM11
DataMed IndexTRIM11
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRIM11
EVEXTRIM11
GoPubMedTRIM11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 15:40:34 CEST 2020
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