TRIM44 (tripartite motif containing 44)

2016-03-01  

Identity

HGNC
LOCATION
11p13
LOCUSID
ALIAS
AN3,DIPB,HSA249128,MC7
FUSION GENES

Other Information

Locus ID:

NCBI: 54765
MIM: 612298
HGNC: 19016
Ensembl: ENSG00000166326

Variants:

dbSNP: 54765
ClinVar: 54765
TCGA: ENSG00000166326
COSMIC: TRIM44

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166326ENST00000299413Q96DX7

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
234607402013Novel function of Trim44 promotes an antiviral response by stabilizing VISA.25
228629692012Overexpression of TRIM44 contributes to malignant outcome in gastric carcinoma.23
277545792017A novel prognostic factor TRIM44 promotes cell proliferation and migration, and inhibits apoptosis in testicular germ cell tumor.23
270584152016TRIM44 promotes proliferation and metastasis in non‑small cell lung cancer via mTOR signaling pathway.21
253455392015Trim44 facilitates the migration and invasion of human lung cancer cells via the NF-κB signaling pathway.17
193588232009TRIM44 interacts with and stabilizes terf, a TRIM ubiquitin E3 ligase.16
288855452017TRIM44 Is a Poor Prognostic Factor for Breast Cancer Patients as a Modulator of NF-κB Signaling.15
294462532018Elevated TRIM44 promotes intrahepatic cholangiocarcinoma progression by inducing cell EMT via MAPK signaling.14
276196782016High expression of TRIM44 is associated with enhanced cell proliferation, migration, invasion, and resistance to doxorubicin in hepatocellular carcinoma.11

Citation

Dessen P

TRIM44 (tripartite motif containing 44)

Atlas Genet Cytogenet Oncol Haematol. 2016-03-01

Online version: http://atlasgeneticsoncology.org/gene/55671/trim44